DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3078 and unc93b1

DIOPT Version :9

Sequence 1:	NP_001356930.1	Gene:	CG3078 / 31211	FlyBaseID:	FBgn0023524	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	XP_012815862.1	Gene:	unc93b1 / 100101743	XenbaseID:	XB-GENE-492943	Length:	604	Species:	Xenopus tropicalis

Alignment Length:	527	Identity:	107/527 - (20%)
Similarity:	206/527 - (39%)	Gaps:	120/527 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 SLAHGLMNCVLLPVMALQGSNAVWHHREEWLPLG-PEVGSLLLSALFLVAAGMSLPSIRLMKRYG 319
            ||...|...|.|.::.:|   .:.|:.|.:..:. ..:|...:.:..|:...:: |.:.|:
Frog    81 SLGAALTYGVYLGLLQMQ---LILHYDETYRDVKYSNIGLQDIDSKMLMGINVT-PIVALL---- 137

  Fly   320 YGPLIVANYMTV-LLFLLSHLYA---------SIYTLLPAYLLLGMTLSGSAGSKAALIVHFGGK 374
            |.|:::..:.|. ::||.|.:||         ..|||:|:..::|:           :||.|...
Frog   138 YTPVLIRFFGTKWMMFLSSGIYALFVSTNYWERYYTLVPSATVIGV-----------MIVPFWAS 191

  Fly   375 LSCSCDSQQSQAAVDVLHEEHKMFCN-RDQKVRRLARWFRVSQDLGLIGGALLASILLACSDGNF 438
            |.         ..:..:.:::..|.| :::.||...|..|.:....:|   :..||..:....:|
Frog   192 LG---------NYITRMAQKYYEFVNYKEENVREQRRVPRGASHRYII---IFQSIFYSLFHISF 244

  Fly   439 TGDCSGLVYYGNESWPPQLRDF---YNRNEHGDRICGA----DMCPLRVQSILEAGWANGSSIPS 496
            ......:.::        |..|   ||......|.|||    .:.|....::|.       ::|.
Frog   245 VLAQLPVHFF--------LSKFFYSYNHTLFNVRDCGAAIQHGILPNFNLTVLH-------TLPP 294

  Fly   497 SIYAGFIESEPRVAGQSLLWLYVLFSMVSLTLSLLIVVDKVQAIGSS-RPERSRDV-SITDTLLF 559
            |:...::||  .:.|.:|         ||:.|.||:       .||: ||....|: ||....:|
Frog   295 SLNLIYVES--ALMGAAL---------VSMLLILLL-------CGSAYRPTEEIDLRSIGWGNIF 341

  Fly   560 AGPL------------AYFV--GTEQAYMMGDFLRAFVTCSLGIGMIAGALIGMGLMQLIVSCTL 610
            ..|.            .||:  |.|..:....|...:..||||:..:...|...|: ....|.:|
Frog   342 QLPFKHARDYRLRCLAPYFLYSGFEVLFACTCFALCYGVCSLGLESLPFLLTAYGI-SASFSSSL 405

  Fly   611 SMLLRHVKRIVVILAGFFFHSCLLLALSSWKPS---SDDSALFYVIAASWGACNGMWETLLLSLV 672
            ::.:....|.:.::.|...|.|:|:.|..|.|:   .....|.|::|..||..:.:.::.|..::
Frog   406 ALCMLRFPRQIPLVGGTLLHCCILIGLFFWSPTPKLQSQKPLLYLVAILWGVGSALNKSGLSIII 470

  Fly   673 TLNHSSHVTE---------VQAPLLALRFLGLGLTFAGHGFLCESMKIIALVVLLVISVPPYATL 728
            .:.:.....:         :||..:.:.:|..|:..        :.|:..::...:|||..|..:
Frog   471 GVFYEDKERQDFVFTIYHWLQALAIFIVYLWSGIPV--------TAKLGIMLASALISVLSYLWM 527

  Fly   729 EIRLEAQ 735
            |.:|..:
Frog   528 EHKLSCK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:354818
CG3078	NP_001356930.1	MFS	<496..731	CDD:355786	56/262 (21%)
unc93b1	XP_012815862.1	MFS_unc93B1	77..533	CDD:340966	107/524 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910