DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3078 and unc93b1

DIOPT Version :9

Sequence 1:	NP_001356930.1	Gene:	CG3078 / 31211	FlyBaseID:	FBgn0023524	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_001275745.1	Gene:	unc93b1 / 100000934	ZFINID:	ZDB-GENE-130424-1	Length:	623	Species:	Danio rerio

Alignment Length:	525	Identity:	106/525 - (20%)
Similarity:	195/525 - (37%)	Gaps:	152/525 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 LGPEVGSLLLSALFLVAAGMSLPSIRLMKRYG-------YG------------------PLIVAN 327
            :|...|.:::.:::     |.|..::|:..|.       ||                  |::...
Zfish    73 VGASCGGMIIYSVY-----MGLLQMQLILHYDETYREVKYGTLGLEDIDNKMLMGINVTPIVGLL 132

  Fly   328 YMTVL---------LFLLSHLYA---------SIYTLLPAYLLLGMTLSGSAGSKAALIVHFGGK 374
            |..||         :||.|.:||         ..|||:|:.:.:|:.:.....|....|..
Zfish   133 YTPVLIRFLGTKWMMFLASGIYALFVSTNYWERYYTLVPSAVAIGVVIVPLWASMGNYITR---- 193

  Fly   375 LSCSCDSQQSQAAVDVLHEEHKMFCN-RDQKVRRLARWFRVSQDLGLIGGALLASILLACSDGNF 438
                            :.:::..|.| :|:.|:...:..:         ||..:.|::..|
Zfish   194 ----------------MAQQYYEFVNYKDENVQEQKKPPK---------GAFHSYIIIFQS---- 229

  Fly   439 TGDCSGLVYY-------GNESWPPQLRDFYNR--NEHGDRICGADMCPLRVQSILEAGWANGS-- 492
                   |:|       ....:|..|  |.|.  |::...:.....|....:.::|    |.:
Zfish   230 -------VFYIIFHLSFVFAEFPTVL--FLNNYLNDYRHTLFKVSQCGAGGKGVIE----NFNKT 281

  Fly   493 ---SIPSSIYAGFIESEPRVAGQSLLWLYVLFSMVSLTLSLLIVVDKVQAIGSSR----P-ERSR 549
               |:|.|:.  .||.|..:.|.:.|.:.:...:..........:| :::||...    | :..|
Zfish   282 VLKSLPRSLL--LIEVESALMGAAFLSMLIFLLLCGAAYRPTEEID-LRSIGWGNIFQLPFKHLR 343

  Fly   550 DVSITDTLLFAGPLAYFVGTEQAYMMGDFLRAFVTCSLGIGMIAGALIGMGLMQLIVSCTLSMLL 614
            |..|  .||.  |...:.|.|..:.:.....::..|::|:..:...::..||...|.| .|::.|
Zfish   344 DYRI--RLLC--PFFIYSGFEVLFAVQGLTLSYGVCAVGMEKLWLLVMVYGLSSSICS-ALALAL 403

  Fly   615 RHVKRIVVILAGFFFHSCLLLALSSWKPS-SDDSALFY--VIAASWGACNGMWETLLLSLV---- 672
            ..:.|.|::|||.|.|..|::||..|.|: .|.|.|.|  |::|.||....:.:|.|.:|:
Zfish   404 LRLPRPVILLAGAFVHFVLIIALMCWSPTPRDTSRLPYLLVVSALWGLGTALNKTGLSTLLGMLY 468

  Fly   673 ----------TLNHSSHVTEVQAPLLALRFLGLGLTFAGHGFLCESMKIIALVVLLVISVPPYAT 727
                      |:.|     ..||..:.:.:|...|....        |:..|::.|:::...|..
Zfish   469 EDKERLDFVYTIYH-----WWQAIAIFIVYLWSALPMRA--------KLGLLLLTLLVASLCYVQ 520

  Fly   728 LEIRL 732
            :|.||
Zfish   521 MERRL 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:354818
CG3078	NP_001356930.1	MFS	<496..731	CDD:355786	60/256 (23%)
unc93b1	NP_001275745.1	MFS	<132..>192	CDD:328737	14/59 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578217
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3097
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.700