Protein Alignment Vinc and alpha-Catr

DIOPT Version :10

• Sequence 1: NP_476820.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Alignment Length: 1028
• Identity: 159/1028 - (15%)
• Similarity: 312/1028 - (30%)
• Gaps: 432/1028 - (42%)

  Fly    45 VVSAAVANLVKVGRDTINSSDDKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIE 109
            :::.||...:.:|.  |.:.::..::.||..|......|.:.:|...|:   .|.||...:..||
  Fly    34 LLNIAVERFITIGE--IIAEENIDIKGDMYEAAKEARDAGKSIERLCDI---SPLSGMELRHHIE 93

  Fly   110 ----------GSRGILQGTSSLLLCFDESEVRKIIQECKRVLDYLAVAEVINTMEQLVQFLKDLS 164
                      .:|.:|...:.:||..|...|:|::...||..:.|   |.:.::....:|::..|
  Fly    94 PLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESL---EKLESVMNFTEFVRAFS 155

  Fly   165 ---------PCLSKVHREVGAREKELTHQVHSEILVRCLEQVKTLAPILICSMKVYIH---IVEQ 217
                     ..|:..||.....|:.......:..::.     |::|.:|..|....||   ::.:
  Fly   156 VFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILE-----KSIAILLTSSKNSLIHSDCVIVK 215

  Fly   218 QGRGA-----------------------------EEAAENRNYLAARMSDELQEIIRVL-----Q 248
            :.|..                             |:.|.|.||....:...::.|:.::     |
  Fly   216 ENRDTVFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQ 280

  Fly   249 LTTY-----------------DED--TSE-----------------------LDNLTVLKKLSNA 271
            ::.|                 |:|  .||                       .::|.:.::||.|
  Fly   281 MSYYEGSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNFRKHLSSESLDLREELSLA 345

  Fly   272 ISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEISERCLPQDSYPIRKLADEVTAMANTLCE 336
            .....|:|:::..:||....  ..|.:....||.                ||  |.....||:.:
  Fly   346 FEKLFEKAHDFTDSPYISHN--HRKNILSYCDNC----------------KL--EFDLYLNTIMK 390

  Fly   337 LRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQGRLEQAVKWLQHPEI 401
            .:.||.|.:.                         ||...|..|    ::||.:        ||:
  Fly   391 DQHEGGGGAG-------------------------GVGGVGGGQ----VKGRSD--------PEL 418

  Fly   402 NDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAAGSGPAAKQAAKQLTQKLY 466
            .                          ..:.:::||                 ||....::.::.
  Fly   419 G--------------------------MLSSLEELC-----------------KQLVVSVSSQIE 440

  Fly   467 ELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRM 531
            :...:::  :.:::|:.|..::|...               ..|.||:|:.   |.|
  Fly   441 DFNESLK--ICSKLVKSFHVLATNYD---------------IDNLNQRSSK---FHD-------- 477

  Fly   532 VAAGGACGN-----KKIAEILLSSAAQVDS---------LTPQLISAGRIRMNYPGSKAADEHLQ 582
                 .|.:     |.:..|..:...||.:         ..||:..|.:|...|..|.||:|:.:
  Fly   478 -----CCDHIFDICKLLQHIAPTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENFE 537

  Fly   583 NLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLIN 647
            :....:                                             |.:  |:.|:.:..
  Fly   538 SFSDMW---------------------------------------------KWL--TNEISMIAK 555

  Fly   648 RVLL-VAKQEADNSEDPVFTERLNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQRLL 711
            ::|: :...:.|...|   .|:..:::::|.:|......|.::|
  Fly   556 KILVSINTTKGDRDAD---AEKCESSSDKLTKSGVPATEDGEMV--------------------- 596

  Fly   712 GDVREVRDAIAPPQPPPLPTSLPPPIPELSALHLSNQNAERAPPRPPLPREGLAPVRPPPPETDD 776
                                       |.|.|...|..
  Fly   597 ---------------------------EYSGLEGKNNG--------------------------- 607

  Fly   777 EDEGVFRTMPHANQPILIAARGLHQEVRQWS---SKDNEIIAAAKR---MAILMARLSELVLSDS 835
             |...:::                    :||   |.||:|:..||.   ||.||.:.::     .
  Fly   608 -DLNTYQS--------------------KWSEDLSDDNDILKRAKNMSAMAFLMYQFTK-----G 646

  Fly   836 RGSKR---ELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVK 897
            .||.|   :|...|:..||.:..:.::.:..:.|......:.:||.:.:|:||....|:.  |||
  Fly   647 NGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQF--TVK 709

  Fly   898 ATMLGAQGSDEDREAT----EMLVGNAQNLMQSVKETVRAAEGASIKIRSDQT 946
            ...:|       :.||    :.::...:|||..:.:.|......:.|.:.:.|
  Fly   710 DHTVG-------KAATFVKVDHVIRETKNLMNVINKVVSKCFECATKYKLNLT 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vinc	NP_476820.1	Vinculin	3..960	CDD:460040	159/1028 (15%)
alpha-Catr	NP_726389.4	Vinculin	38..755	CDD:460040	158/1022 (15%)