Protein Alignment Vinc and alpha-Cat

DIOPT Version :10

• Sequence 1: NP_476820.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_524219.1
• Gene: alpha-Cat / 40517
• FlyBaseID: FBgn0010215
• Length: 917
• Species: Drosophila melanogaster
• Alignment Length: 991
• Identity: 217/991 - (21%)
• Similarity: 387/991 - (39%)
• Gaps: 184/991 - (18%)

  Fly     6 TKTIESILDPVAQQVSRLVILH--EEAEDGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSDDKI 68
            |.::|..|:|:..||:.||...  .:.:.|.: ...|..|..|..|..|.::.|......:.|
  Fly    29 TMSVEKTLEPLVLQVTTLVNTKGPSKKKKGKS-KRASALVAAVEKATENFIQKGEQIAYENPD-- 90

  Fly    69 LRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKI 133
            :.|:|.:|:..|:.....:..|:.....||.|...|..::..:|.:|...:.||:..|..:|..:
  Fly    91 ITQEMLTAVDEVKKTGDAMSIAAREFSEDPCSSLKRGNMVRAARNLLSAVTRLLILADMVDVHLL 155

  Fly   134 IQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQVK 198
            ::....|.|.|...:..::.::|:..::.......::.::...|::||......:.|......:|
  Fly   156 LKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKRQQELKDPQLRDDLAAARAMLK 220

  Fly   199 TLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSELDNLT 263
            ..:.:|:.:.|||:...|     .:.|..||::
  Fly   221 KHSTMLLTASKVYVRHPE-----LDLAKVNRDF-------------------------------- 248

  Fly   264 VLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQ-------VIDNATEISERCLPQDSYPIR 321
            :||::.:|::...:.|....|.|..:..|.||.|...       |:|..|...:|.        |
  Fly   249 ILKQVCDAVNTISDVAQGKSSQPTDIYSGAGELAAALDDFDEGIVMDPMTYSEKRS--------R 305

  Fly   322 KLADEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQ 386
            :|.:|                                  .|:|::..|.|..|.
  Fly   306 QLLEE----------------------------------RLESIISAAALMADA----------- 325

  Fly   387 GRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAAGSG 451
                            |....||...::.|        |...::| :|.|..|......|...|
  Fly   326 ----------------DCTRDERRERIVAE--------CNAVRQA-LQDLLSEYMSNMSQKDNS- 364

  Fly   452 PAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSN 516
            |...:|..|:.:|..:|:..::.|:|:.:...|::.:|||....||     ...|.|:...:||.
  Fly   365 PGLSRAIDQMCRKTRDLRRQLRKAVVDHVSDSFLETTTPLLDLIEA-----AKSGNEKKVREKSE 424

  Fly   517 NLQAFSDRASKTSRMVAAGGACGNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAADEHL 581
            .....:::..:.:.:|.:  ...|:...:::..:|||::||.||:|:|..|....|.||.|.|::
  Fly   425 IFTKHAEKLVEVANLVCS--MSNNEDGVKMVRYAAAQIESLCPQVINAASILTVRPNSKVAQENM 487

  Fly   582 QNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLI 646
            ...:|.:...|..:....|..|...||:..||.|:......|..|:.....:.:......|....
  Fly   488 TTYRQAWEVQVRILTEAVDDITTIDDFLAVSENHILEDVNKCVMALQVGDARDLRATAGAIQGRS 552

  Fly   647 NRVLLVAKQEADNSEDPVFTERLNAAAN--------RLERSLPAMVGDAKLVATNIADPAAAAAW 703
            :||..|.:.|.||.|..::|:|:..|..        :.::.:.|.||.....:....|
  Fly   553 SRVCNVVEAEMDNYEPCIYTKRVLEAVKVLRDQVMMKFDQRVGAAVGALSNNSNKDVD------- 610

  Fly   704 KNSF---QRLLGD-VREVRDAIAPPQ-PPPLPTSLP-PPIPEL-------SALHLSNQNAERAPP 755
            :|.|   .||:.| |||:|.|:...: ...|.|... .|:.:|       |:.|..:|..:..|
  Fly   611 ENDFIDASRLVYDGVREIRRAVLMNRSSEDLDTDTEFEPVEDLTLETRSRSSAHTGDQTVDEYP- 674

  Fly   756 RPPLPREGLAPVRPPPPETDDEDEGVFRTMPHANQPILIAARGL--HQEVRQWSSKDNEIIAAAK 818
                ...|:...|....:..:||:     ...|.|..|.....|  ..||.:|....|:||..||
  Fly   675 ----DISGICTAREAMRKMTEEDK-----QKIAQQVELFRREKLTFDSEVAKWDDTGNDIIFLAK 730

  Fly   819 RMAILMARLSELVLSDSRG---SKRELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVC 880
            .|.::|..:::  .:..||   :..::|..||||:||...:.:|.:|:|.||.:...:.:||...
  Fly   731 HMCMIMMEMTD--FTRGRGPLKTTMDVINAAKKISEAGTKLDKLTREIAEQCPESSTKKDLLAYL 793

  Fly   881 ERIPTIGTQLKILSTVKATMLGAQGS--DEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRS 943
            :||.....|::|.|.|||.:....|.  ....::...|:..|:|||.:|..||:.:..||.|...
  Fly   794 QRIALYCHQIQITSKVKADVQNISGELIVSGLDSATSLIQAAKNLMNAVVLTVKYSYVASTKYTR 858

  Fly   944 DQT--SNRLQWVRRQP 957
            ..|  |..:.|..:.|
  Fly   859 QGTVSSPIVVWKMKAP 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vinc	NP_476820.1	Vinculin	3..960	CDD:460040	217/991 (22%)
alpha-Cat	NP_524219.1	Vinculin	26..877	CDD:460040	217/991 (22%)