Protein Alignment Vinc and ctnna1

DIOPT Version :10

• Sequence 1: NP_476820.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_571531.1
• Gene: ctnna1 / 30741
• ZFINID: ZDB-GENE-991207-24
• Length: 907
• Species: Danio rerio
• Alignment Length: 1009
• Identity: 217/1009 - (21%)
• Similarity: 388/1009 - (38%)
• Gaps: 223/1009 - (22%)

  Fly     6 TKTIESILDPVAQQVSRLVILHEEAEDG--NAMPDLSRPVQVVSAAV----ANLVKVGRDTINSS 64
            |..:|.:|:|:..||:.||   ..:..|  |.....|:...|::|:|    .|.::.|...  :.
Zfish    22 TLAVERLLEPLVTQVTTLV---NSSNKGPSNKKKGRSKKAHVLAASVDEATQNFLEKGEKI--AK 81

  Fly    65 DDKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESE 129
            :.:.|::::.:|:..|....:.::.||.....||.|...|..::..:|.:|...:.||:..|.::
Zfish    82 ESQFLKEELTAAVEDVRKQGESMKMASGEFAEDPCSSVKRGNMVRAARALLSAVTHLLVLADMAD 146

  Fly   130 VRKIIQECKRVLDYLAVAEVINTMEQL-VQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRC 193
            |.:::.:.|.|.:.|.......|.:.| :|: |.|.|.:.|::.....|::||....|.:.:...
Zfish   147 VYQLLLQLKLVEENLMKVRNAGTEQDLGIQY-KALKPEVDKLNMMAAKRQQELKDVHHKDQMAAA 210

  Fly   194 LEQVKTLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSE 258
            ...::...|:|                          |.|:|..           |...|....:
Zfish   211 RGVLQRNVPML--------------------------YTASRAC-----------LQHPDVAAYK 238

  Fly   259 LDNLTVLKKLSNAIS--NKMEQANEWLSNPYALRGGVGEKAL------RQVIDNATEIS-ERCLP 314
            .:...:.|:|.:|:|  :...||.....:.::...|.||.|.      :|:|.:....| ||..|
Zfish   239 ANRDLIYKQLQHAVSGISNAAQATSSEDSSFSQTAGGGELAYALNNFDKQIIVDPLSFSEERFRP 303

  Fly   315 QDSYPIRKLADEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQ 379
            .....:..:......||::.|......:....:..|:.:.::|.:.|...
Zfish   304 SLEERLESIISGAALMADSSCTRDDRRERIVAECNSVRQALQDLLSEYMG--------------- 353

  Fly   380 QTAHTIQGRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLK 444
                                                ..|||        :|::
Zfish   354 ------------------------------------NAGRK--------EKSD------------ 362

  Fly   445 RQAAGSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQ 509
                    |...|..::|:|..:|:..::.|:::.:...|::.:.||....||.          :
Zfish   363 --------ALNTAIDRMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAA----------K 409

  Fly   510 NFNQK--SNNLQAFSDRASKTSRMVAAGGAC---GNKKIAEILLSSAAQVDSLTPQLISAGRIRM 569
            |.|:|  ....|.|.:.|:|.  :..|..||   .|::..:::..:|:|:::|.||:|:|.....
Zfish   410 NGNEKEVKEYAQVFREHANKL--IEVANLACSISNNEEGVKLVRMAASQLETLCPQVINAALALA 472

  Fly   570 NYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQK 634
            ..|.||.|.:::...|.|:...|..:....|..|...||:..||.|:......|..|:.    :|
Zfish   473 AKPNSKVAQDNMDLFKDQWEKQVRVLTDAVDDITSIDDFLCVSENHILEDVNKCVIALQ----EK 533

  Fly   635 MVDNTSNIARLIN----RVLLVAKQEADNSEDPVFTERLNAAANRL-ERSLPAMVGDAKLVATNI 694
            .||.....|..|.    ||:.|...|.||....|:||::..|...| |..:|......:.....:
Zfish   534 DVDGLDRTAGAIRGRAARVVHVVTSEMDNYMPGVYTEKVLEATKLLTETVMPRFTEQVEAAVEAL 598

  Fly   695 ADPAAAAAWKNSF---QRLLGD-VREVRDAIAPPQPPP---------------LPTSLPPPIPEL 740
            :........:|.|   .||:.| ||::|.|:...:.|.               ..||:.....:|
Zfish   599 SANNGQPVDENEFIDASRLVYDGVRDIRKAVLMIRTPEELDDSDFETEDFDSRSRTSVQTEDDQL 663

  Fly   741 SALHLSNQNAERAPPRPPLPREGLAPVRPPPPETDDEDEGVFRTMPHANQPILIAARGLHQEVRQ 805
                ::.|:|.....:  ||:|..|.:........:|..                  .|..||.:
Zfish   664 ----IAGQSARAIMAQ--LPQEQKAKIAEQVASFQEEKS------------------KLDAEVSK 704

  Fly   806 WSSKDNEIIAAAKRMAILMARLSELVLSDSRG-----SKRELIATAKKIAEASEDVTRLAKELAR 865
            |....|:||..||:|.::|..:::.    :||     :..::|:.|||||||...:.:|.:.:|.
Zfish   705 WDDSGNDIIVLAKQMCMIMMEMTDF----TRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRAIAD 765

  Fly   866 QCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATM--LGAQGSDEDREATEMLVGNAQNLMQSVK 928
            ||.|...:.:||...:||.....||.|.|.|||.:  ||.:......::...|:..|:|||.||.
Zfish   766 QCPDSACKQDLLAYLQRIALFCHQLNICSKVKAEVQNLGGELVVSGLDSAMSLIQAAKNLMNSVV 830

  Fly   929 ETVRAAEGASIKIRSDQTSNRL-----QWVRRQP 957
            .||:|:..||.|.:..|....|     .|..:.|
Zfish   831 STVKASYVASTKYQKSQDMQSLNMPAISWKMKAP 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vinc	NP_476820.1	Vinculin	3..960	CDD:460040	217/1009 (22%)
ctnna1	NP_571531.1	Vinculin	19..867	CDD:460040	217/1009 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	870..895