Protein Alignment Vinc and Vinc

DIOPT Version :10

• Sequence 1: NP_476820.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: XP_061501594.1
• Gene: Vinc / 1269702
• VectorBaseID: AGAMI1_012757
• Length: 965
• Species: Anopheles gambiae
• Alignment Length: 975
• Identity: 732/975 - (75%)
• Similarity: 844/975 - (86%)
• Gaps: 24/975 - (2%)

  Fly     1 MPVFHTKTIESILDPVAQQVSRLVILHEEAEDGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSD 65
            |||||||||||||:|||||||||||||||||||||||||.:|||.||.||.|||:|||:||.:||
Mosquito     1 MPVFHTKTIESILEPVAQQVSRLVILHEEAEDGNAMPDLGKPVQAVSVAVTNLVRVGRETIQNSD 65

  Fly    66 DKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEV 130
            |.||:||||::|.|||.|:|||||||.||||||:|||||||||||||||||||||||||||||||
Mosquito    66 DDILKQDMPASLTRVETAAQLLEEASLMLRSDPFSGPARKKLIEGSRGILQGTSSLLLCFDESEV 130

  Fly   131 RKIIQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLE 195
            |||::|||||||||||:|||::||.|||||||||||||||..:||||||||||||||||||||||
Mosquito   131 RKIVRECKRVLDYLAVSEVIDSMEDLVQFLKDLSPCLSKVTAQVGAREKELTHQVHSEILVRCLE 195

  Fly   196 QVKTLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSELD 260
            |:|.|||||||||||||.|.||.|:|:|||||||||||:|||:|||||||||||||||||.||||
Mosquito   196 QLKILAPILICSMKVYILIAEQSGKGSEEAAENRNYLASRMSEELQEIIRVLQLTTYDEDQSELD 260

  Fly   261 NLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEISERCLPQDSYPIRKLAD 325
            |||||||:.|||.||:|.|||||.||||||||||||||||:::|..::::|||||||:.:||||.
Mosquito   261 NLTVLKKIQNAIRNKLEAANEWLRNPYALRGGVGEKALRQIVENGLKVADRCLPQDSHILRKLAG 325

  Fly   326 EVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQGRLE 390
            ::|||.||||:|||||||.:|.|:::.|.|||::|.|...|..|::||||||:||||||:|||||
Mosquito   326 DITAMTNTLCDLRQEGKGTTPHADNIARDIRDKLGSLDQSVLNAIMGVDKAGLQQTAHTVQGRLE 390

  Fly   391 QAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLK-------RQAA 448
            ||.:|||:|..:|.|||.|||.|||:|||:||:|..||||||:.|||||||:|.       ....
Mosquito   391 QACRWLQNPARDDRGLGVRAIALIVDEGRRVADGLGGHQKAEMAQLCDEVEQLAHDFSQMCNNGL 455

  Fly   449 GSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQ 513
            |..|.|::.|::|.:||:.||..||:|:|||:|:||:|:|||||||.|||.||||||||||||||
Mosquito   456 GHTPQAQELARRLNEKLHGLKKQIQDAVVNRVVEDFIDISTPLKQFMEAVAQPEGTPGREQNFNQ 520

  Fly   514 KSNNLQAFSDRASKTSRMVAAGGACGNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAAD 578
            |||.|||||:|||||||||||||:.||||:||.||:||.|:|||||||:||||||||||.||||:
Mosquito   521 KSNRLQAFSNRASKTSRMVAAGGSGGNKKLAEGLLASANQIDSLTPQLVSAGRIRMNYPTSKAAE 585

  Fly   579 EHLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIA 643
            |||.|||||||||:|||||||||||||||||:.||:.||.::.||:|||..|||||||||||:.|
Mosquito   586 EHLNNLKQQYADTILRMRTLCDQATDPADFIEASEKQMQKHSFLCDDAIRTRQPQKMVDNTSSEA 650

  Fly   644 RLINRVLLVAKQEADNSEDPVFTERLNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQ 708
            ||.|||||||||||||||||.:.:|||.|:::|:.|:..||.:||.|:|||:||.||:.|:.:.:
Mosquito   651 RLANRVLLVAKQEADNSEDPEYIDRLNGASDQLQASISPMVQEAKNVSTNISDPIAASNWREANR 715

  Fly   709 RLLGDVREVRDAIAPPQPPPLPTSLP--PPIPELSALHLSNQNAERA-PPRPPLPREGLAPVRPP 770
            .||..||.||.|:         |..|  |.:|:||.|.|...:.|.. |||||||||.:.|:|||
Mosquito   716 ALLQSVRNVRGAV---------THAPTVPEMPDLSQLQLGGGSHEVVPPPRPPLPRENVPPMRPP 771

  Fly   771 PP--ETDDEDEGVFR--TMPHANQPILIAARGLHQEVRQWSSKDNEIIAAAKRMAILMARLSELV 831
            ||  ||||||: ||:  :|||||||||:||.||||||||||||||||||||||||:|||||||||
Mosquito   772 PPVAETDDEDD-VFQAGSMPHANQPILMAAHGLHQEVRQWSSKDNEIIAAAKRMAVLMARLSELV 835

  Fly   832 LSDSRGSKRELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTV 896
            .:||:|||||||||||:|||||||||||||:|||||||:||||||||||||||||||||||||||
Mosquito   836 RADSKGSKRELIATAKQIAEASEDVTRLAKQLARQCTDKRIRTNLLQVCERIPTIGTQLKILSTV 900

  Fly   897 KATMLGAQGSDEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTSNRLQWVRRQPWYQY 961
            ||||||||||:|||||||||||||||||||||||||||||||||||||||:.||:||||||||||
Mosquito   901 KATMLGAQGSEEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTNQRLRWVRRQPWYQY 965

  Fly   962  961
            Mosquito   966  965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vinc	NP_476820.1	Vinculin	3..960	CDD:460040	727/970 (75%)
Vinc	XP_061501594.1	None