Protein Alignment ph-p and phc3

DIOPT Version :10

• Sequence 1: NP_476871.2
• Gene: ph-p / 31181
• FlyBaseID: FBgn0004861
• Length: 1589
• Species: Drosophila melanogaster
• Sequence 2: NP_001430217.1
• Gene: phc3 / 558094
• ZFINID: ZDB-GENE-070912-369
• Length: 890
• Species: Danio rerio
• Alignment Length: 1114
• Identity: 252/1114 - (22%)
• Similarity: 376/1114 - (33%)
• Gaps: 339/1114 - (30%)

  Fly   569 RNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQ 633
            |.:.:|..|:......||.|..| ...|...|::......:.....|...|....|.:......|
Zfish     9 REELEGDGGVTTASTTATSTTPT-GTSIPSGNISSDRQAVQVIQQTLHRPQSMTAQYLQQMYAAQ 72

  Fly   634 QQQLAVATAQLQQQ---QQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTA-QNQSLLKAKMRN 694
            ||.:.:.||.||||   ||.|||..:..........||.|...:.|.|...| |..::.:..:..
Zfish    73 QQHILLQTAALQQQQQHQQNLTATQILTTTDMAAQTNGRQFTSSPSSSNGNAPQLANVTQTSIPI 137

  Fly   695 KQQPVRPALATLKTEI-----GQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGT 754
            ...||...:|.::...     |.::.|..::|:.:....|.|.....|        |:::    |
Zfish   138 PTSPVTQPMARIQVTSSSSTGGDISQQAMLLGNSSPTGSQAQMYLRTQ--------MLIL----T 190

  Fly   755 PITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQ-QQQQ 818
            |          |||.|.|     |..|.....|..|....|.|..|::.....|...:|. |.:.
Zfish   191 P----------AATVAAV-----QPDLTVVSSISSQSASSQVQSLALRTHLPGALTTSQNIQIKP 240

  Fly   819 QVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQIL---QVAPNQ 880
            .:..|..|:...:.::...:.  .|..|...|..:.|:        .|.|.||...   .:.|:.
Zfish   241 PLQGQTLVSPPPKMSICPLKS--TQLPQNLVETSRSVS--------VLNNVTQTPSAQPAIPPST 295

  Fly   881 F--ITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGAT 943
            |  :.||          |||:.||...:..:|..                    |.:::|||.:|
Zfish   296 FTPVQSH----------QLIRHQLHCPSGPRVAP--------------------QHLIIQQSSST 330

  Fly   944 SQQTSQQQQHHQSGQLQL-------SSVPFSVSSSTTPAGIATSSALQAALSASGAIFQTAKPGT 1001
                     |.|...:.|       |..||::.:.|||......|.....||...:..|||..
Zfish   331 ---------HRQLHPITLRVTAQDGSPTPFTLQTRTTPTTATVQSQQTELLSVPSSTNQTANQ-- 384

  Fly  1002 CSSSSPTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQGPP-S 1065
                         |..:|.|.|.                                   |..|| .
Zfish   385 -------------TKYTSPPAVL-----------------------------------PDPPPLH 401

  Fly  1066 LTPTTNPILAMTSMMNATVGHLSTAPPVTV---------SVTSTAVTSSPGQLVLLSTASSGGGG 1121
            |.|...|:...|.        ||..||:.:         ||.:..|.|..   .|||..
Zfish   402 LGPALEPVSQYTP--------LSCPPPLKLVQPQRLALRSVQAVEVQSDH---TLLSEE------ 449

  Fly  1122 SIPAT------PTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEA 1180
            .:|.|      |.:..|.....|..:.: .|.|...........:|.....|:.:..||......
Zfish   450 ELPLTEAVLQLPFQSLPPPQTVAVDLKV-QPATQTEASQVTPLLESVNLTLVTDAEHASPPQNSR 513

  Fly  1181 LSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNS---VSGKEEPKLATCGSLTSATSTST 1242
            .|:.....||..|.:.:...|.:..|..........|:|   :...|||        |.||| |.
Zfish   514 TSSSPTLSRSDEPQRSSDVVTDQPENLTADQEQPCVPSSRSVIRSPEEP--------THATS-SP 569

  Fly  1243 TTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLP-KAMIKPNVL 1306
            :..:::.:     .:|:.:|:||...:..|.                       | :|:.:|::|
Zfish   570 SPLLSSAV-----RSSSRLSSASLPESPEGR-----------------------PSQAISRPHIL 606

  Fly  1307 THVIDGFIIQEANEPFPVTRQRYA-------------------------------DKDVSDEPPK 1340
            ||:|:||:|:|..|||||   |:|                               |.|:.|...:
Zfish   607 THLIEGFVIREGLEPFPV---RHASLEMNLQATLPENREDGESALIDADHPDSSSDSDIDDPLAE 668

  Fly  1341 KKATMQEDIKLSGIASAPGSDMVACEQCGKME-HKAKLKRKRYCSPGCSRQ-------------- 1390
            .:.|::   ||        .:::.||.|||.. .:|.|:.||:||..|:|:
Zfish   669 DEQTVE---KL--------PEVLECEFCGKRGLAQAFLRSKRFCSMTCARRFNLRCKKRLNRLRE 722

  Fly  1391 --------AKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPIL 1447
                    ...|..|..|...||            :..:.|.....:...|......:|.|..:.
Zfish   723 EKVTYWPHRSMGKRGRPSRCLNG------------SAREHLPRPQLQGSHQASDNQMVSNSVWME 775

  Fly  1448 GASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLA----------PLSVVTSGAAPKSSEV 1502
            ....|.||                    .|::..|...|          ..|.|.|.:   |||:
Zfish   776 REEEEDPP--------------------GPMTTRLRLQAEREKEQNREQEQSRVESSS---SSEL 817

  Fly  1503 NGTDRPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKI 1567
            .....|  |.|||:.|.:||..||||.|...:|..|||||||||||.|.||::||.:||||||||
Zfish   818 LLDSSP--SQWSVEQVCSFISTLPGCHDVAAEFGCQEIDGQALLLLTEDHLMSAMNLKLGPALKI 880

  Fly  1568 VAKVESIKE 1576
            .|.:.::|:
Zfish   881 CAHINTLKQ 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	DUF5585	1015..>1232	CDD:465521	44/235 (19%)
		SAM_Ph1,2,3	1508..1576	CDD:188976	39/67 (58%)
phc3	NP_001430217.1	None