Protein Alignment ph-p and phc1

DIOPT Version :9

• Sequence 1: NP_476871.2
• Gene: ph-p / 31181
• FlyBaseID: FBgn0004861
• Length: 1589
• Species: Drosophila melanogaster
• Sequence 2: XP_005158395.1
• Gene: phc1 / 403008
• ZFINID: ZDB-GENE-081022-39
• Length: 901
• Species: Danio rerio
• Alignment Length: 1100
• Identity: 268/1100 - (24%)
• Similarity: 400/1100 - (36%)
• Gaps: 314/1100 - (28%)

  Fly   570 NQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQ 634
            ::|.....|.:.::.|.|.||..|.|                     |...|..||:     ..|
Zfish    23 SRPPQIAQMSLYERQAVQALQALQRQ---------------------PNAAQYFQQL-----MLQ 61

  Fly   635 QQLAVATAQLQQ--QQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKA--KMRNK 695
            ||:..||.||..  ..||.|.||.::..:|    |.:..:|.|  |.|...|.|...|  .|.|
Zfish    62 QQINSATCQLHNLAAVQQATLAASRQSSSP----NNSASQPTS--SAQCTVNLSTTSAGGTMTN- 119

  Fly   696 QQPVRPALATLKTEIGQ--VAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITL 758
            .:|:.||.:...|.:.|  :.|.|       :..|.|....:.:.:.|.....::....||
Zfish   120 PRPIGPATSAASTALSQSVLLGGN-------SGGQGQMYLRVNRSLRAPLTPQLIFMPGGT---- 173

  Fly   759 QNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQ 823
               .|...||.|....|||.          |||.         |.||||.|.......|   |..
Zfish   174 ---ATATVATVAQTQPQQQP----------QQQP---------QQQQQQEATPTSSSSQ---SDN 213

  Fly   824 QQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQ 888
            .||.....:.|:..:.|..:.:...|::.........|.|             .|.||..|.||
Zfish   214 DQVQNLAMRCVSTPRAATVKTEFADRKETTGTFPLNQQTQ-------------TPQQFGQSTQQ- 264

  Fly   889 QQQQLHNQLIQQQLQQQAQAQVQA-------QVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQ 946
                     :|.|.|..|.|::|:       .|.|...:...|        ..:..||:||:|..
Zfish   265 ---------VQPQTQPLANAKLQSFSNTANPSVPALNVKPTNQ--------SAVAPQQAGASSNP 312

  Fly   947 TSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSS----P 1007
            .                     |||.||: :..|   |..||.||.......||:.::.:    |
Zfish   313 P---------------------SSSPTPS-LPLS---QLLLSQSGLHQTRGVPGSTATVTHILVP 352

  Fly  1008 TSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQH--QQLISATIAGGT-------------- 1056
            ||:|.|.|  ...||.|.:|.::: .|||...|..|.  ..|.:..:|.||
Zfish   353 TSNVPTST--QGYPLGTVATKSNM-TAQTLVVQPLQQTGANLSTEKLAHGTGHVPIQPKTAQGHR 414

  Fly  1057 ---QQQPQGPPSLTPT----------TNPILAMTSMMNATVGHLSTAPPVTVSVTSTAVT----- 1103
               |..|:.||.:.|.          .:|......::.|....|..:..:.::...|..:
Zfish   415 VPVQMSPRHPPPILPAPPNNGQATAGLHPPHVPVQLVGARQSTLGNSQALALAQARTCCSQQDGT 479

  Fly  1104 -----SSPGQLVLLSTA--SSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKS 1161
                 ::||.:|.:.||  :||.|..:..           ..:.:||...:|..|     .....
Zfish   480 AAVGVNNPGNVVTMVTAMDTSGAGMCLKT-----------AQSALPISQMQTNQS-----AVLSQ 528

  Fly  1162 STPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEP 1226
            ..||:|:.|::..:::|::|....|    ....|.|..|..::|.:.:....|..|  :||  .|
Zfish   529 GNPASVTHSMDGQNNSGDSLFVQSA----QAQIKPAIGPIKRKSESDLTHEISNEP--ISG--SP 585

  Fly  1227 KLA-TCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSIS 1290
            .:. :...|:.|.|..|...|             |.|:..|.:          .|..........
Zfish   586 SMQDSAPPLSPAPSLDTVPEI-------------AFSSPPTLS----------LSLPLPLPRGAG 627

  Fly  1291 NGSK-DLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGI 1354
            .|.: .:|:|::||.||||:|:||:|||..||||||...   |::|...|  .....|||:
Zfish   628 QGDRAPVPQAVVKPQVLTHLIEGFVIQEGAEPFPVTGPL---KELSGAVP--PILHPEDIR---- 683

  Fly  1355 ASAPGSDMVACEQCGKMEHKAKLKR-KRYCSPGCSR----------QAKNGIGGVGSGETNGLGT 1408
                 ||.:.||.|......::.:| ||:|:..||:          :|..|:.|...      ..
Zfish   684 -----SDKLKCEYCLNFAPASQFRRSKRFCTISCSKRYNVSFRNHLRASRGLEGAER------PA 737

  Fly  1409 GGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQA----------- 1462
            ||.|..|.:|               ....|:.|.|..   |..::....|||:.
Zfish   738 GGPVVQDVIA---------------RRRAPRRSSSEI---ACAKITGRHLPVKCRSESSRSDDIS 784

  Fly  1463 -----------AISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAPKSSEVNGTDRPPISSWSVD 1516
                       ::|..|..:.|..:.....|...||      |..|.......:..|  :.|||.
Zfish   785 SCEGEEEEDFLSLSPSSTFSCPRPTHCGPQLDDTAP------GGLPVDENHFLSGNP--ADWSVQ 841

  Fly  1517 DVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKE 1576
            :|..||..|.||:|....|:.||||||||:||||:||::.|.:||||||||.|.:.|:::
Zfish   842 EVCQFISSLQGCEDLASQFLSQEIDGQALMLLKEEHLMSTMNIKLGPALKICASINSLRD 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	SAM_Ph1,2,3	1508..1576	CDD:188976	37/67 (55%)
		SAM	1511..1576	CDD:197735	36/64 (56%)
phc1	XP_005158395.1	PHC2_SAM_assoc	<763..832	CDD:293222	11/74 (15%)
		SAM_Ph1,2,3	834..901	CDD:188976	37/68 (54%)
		SAM	835..901	CDD:197735	37/67 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	88	1.000	Domainoid score	I7895
eggNOG	1	0.900	-	-		E1_28JS2
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6612
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12247
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4720
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.900