Protein Alignment ph-p and Phc2

DIOPT Version :10

• Sequence 1: NP_476871.2
• Gene: ph-p / 31181
• FlyBaseID: FBgn0004861
• Length: 1589
• Species: Drosophila melanogaster
• Sequence 2: NP_001013187.2
• Gene: Phc2 / 313038
• RGDID: 1307912
• Length: 850
• Species: Rattus norvegicus
• Alignment Length: 953
• Identity: 252/953 - (26%)
• Similarity: 378/953 - (39%)
• Gaps: 224/953 - (23%)

  Fly   738 VVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQ--QQQLQLF------QKQQILQQQQML 794
            |.:.:....:..:|:||     |..:..::::.|...:  ..|:.::      |..|::||....
  Rat     7 VPHTSSRASITTNTSGT-----NSSSGCSSSSGGGSGRPTAPQISVYSGIPDRQTVQVIQQALHR 66

  Fly   795 QQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQV-AQA 858
            |...||..:||..||.|.....|....|||.:::.|.|::|..|||...|.:|.......| :||
  Rat    67 QPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVANRQGSTSGSSVSSQA 131

  Fly   859 QAQHQQ---ALANATQQILQVAP--NQFITSHQQQQQQQLHN----QLIQQQLQQQAQAQ----- 909
            .||...   |.:.|..|::..|.  |....|...||...|.|    .|...|.|...:||
  Rat   132 PAQSSSLNLAASPAAAQLINRAQSVNSATASGLAQQAVLLGNTSSPALTASQAQMYLRAQMLIFT 196

  Fly   910 -------VQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFS 967
                   ||.::...:..:.....|.||:               |.:.||...:.....:|.|
  Rat   197 PTATVATVQPELGTGSPARPPTPAQVQNL---------------TLRTQQTPAAAAAAAASGP-- 244

  Fly   968 VSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSS------ 1026
              :.|.|  :..|.||:...|:|..:..|.:..|....||..:..::|:..:.||.|..
  Rat   245 --APTQP--VLPSLALKPTPSSSQPLPPTPQGRTVVQGSPVGAKPSVTDNVTEPLKTDGNSNMEA 305

  Fly  1027 ----------TVASIQQAQTQSAQVHQHQQLISAT--------IAGGTQQQPQGPPSLTP--TTN 1071
                      |||:.|.......|:..||.|...:        :|   ||||| ||..||  .:.
  Rat   306 RPGPDRATVPTVATHQLTAPAYTQLQPHQLLPQPSSKHPQPQFVA---QQQPQ-PPRPTPQVQSQ 366

  Fly  1072 PILAMTS----MMNATVGHLSTAPPVTVSV---TSTAVTSSPG--QLVLLSTASSGGGGSIPATP 1127
            |.||..|    :..:..||.....|||.::   .|||....||  |...|.|..||.....|
  Rat   367 PQLAAVSPSLALQPSPEGHAMPLGPVTQALPLQCSTAHVHKPGSSQQCHLPTPDSGSQNGHP--- 428

  Fly  1128 TKETPSKGP------TATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDA 1186
              |..|..|      |:.::....|.:||        |:...|......|.|..|.
  Rat   429 --EGVSHAPQRRFQHTSAVILQLQPASPV--------PQQCAPDDWKEVVPAEKSV--------- 474

  Fly  1187 SDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIG 1251
                     ..|.|.......|:   .:..|..:.|.:.|.:..|    .|..|        |.|
  Rat   475 ---------PVTRPGLSPHQQAI---ITAIPGGLPGPKSPNIQQC----PAHET--------GQG 515

  Fly  1252 VARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQ 1316
            :..         |.|..:|.|....:..|.::.|.::..||....|:|::||.:|||||:||:||
  Rat   516 IVH---------ALTDLSSPGMTSGNGNSASSITGTAPQNGENKPPQAIVKPQILTHVIEGFVIQ 571

  Fly  1317 EANEPFPVTR---------QRYADKDVSDEPPKKKATMQEDIKLS----GIASAPGSDM-VACEQ 1367
            |..|||||.|         ::||...:.::.|::..|...|.::.    ..:...|:.: :.||.
  Rat   572 EGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCEL 636

  Fly  1368 CGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEK 1431
            ||:::...|.|| ||:||..|:::.     .||..:..||...           ||       .|
  Rat   637 CGRVDFAYKFKRSKRFCSMACAKRY-----NVGCTKRVGLFHS-----------DR-------SK 678

  Fly  1432 MQTEATPKLSE------SFPILGASTEVPP---MSLPVQAAIS-APSPLAMPLGSPLSVALPTLA 1486
            :|...|...:.      |.|.|...|:..|   :.|.|.||:. |.|.......|..|.....|:
  Rat   679 LQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAHSQEDSSRCSDNSSYEEPLS 743

  Fly  1487 PLSVVTSGAAPKS-------SEVNGTD-----------RPPISSWSVDDVSNFIRELPGCQDYVD 1533
            |:|..:|.:..:.       |:::..|           .|  :.|:|:||..|||.|||||:..:
  Rat   744 PISASSSTSRRRQGQRDLELSDMHMRDLVGMGHHFLPSEP--TKWNVEDVYEFIRSLPGCQEIAE 806

  Fly  1534 DFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKE 1576
            :|..|||||||||||||.||::||.:||||||||.|::..:|:
  Rat   807 EFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKD 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	DUF5585	1015..>1232	CDD:465521	60/257 (23%)
		SAM_Ph1,2,3	1508..1576	CDD:188976	40/67 (60%)
Phc2	NP_001013187.2	Herpes_BLLF1	<141..559	CDD:282904	112/497 (23%)
		PHC2_SAM_assoc	662..781	CDD:465202	28/136 (21%)
		SAM_Ph1,2,3	781..849	CDD:188976	40/69 (58%)