DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ph-p and Samd11

DIOPT Version :9

Sequence 1:	NP_476871.2	Gene:	ph-p / 31181	FlyBaseID:	FBgn0004861	Length:	1589	Species:	Drosophila melanogaster
Sequence 2:	XP_006538909.1	Gene:	Samd11 / 231004	MGIID:	2446220	Length:	558	Species:	Mus musculus

Alignment Length:	554	Identity:	130/554 - (23%)
Similarity:	188/554 - (33%)	Gaps:	177/554 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1129 KETPSKGPTAT-LVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASS--STGEALSNGDASDRS 1190
            |:..||.|.|| |:|         ..::...|:......:||..||||  .|......|
Mouse    43 KKARSKDPQATSLLP---------ELESTMAPEDHYHQLMSALSEASSFEETQRLYHLG------ 92

  Fly  1191 STPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLAT----CGSLTSATSTSTTTTITNGIG 1251
             .||.| ..||  .....:.||.|   :.:..::|...||    .|......|::.......|:.
Mouse    93 -IPSHG-IEPT--YQGGPLSPPFS---DLLRVRQEVATATLRGPSGLEVHLPSSTADHRRKQGLV 150

  Fly  1252 VARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQ 1316
            ..|..|..|.:|                        |.|......|..::.|....|:.   :..
Mouse   151 QRREGAVPAAAT------------------------SFSEREMSQPPPLLSPQNAAHIT---MSS 188

  Fly  1317 EANEPF---PVTRQRYADKDVSDEP-----PKKKATM----QEDIKLSGIASAPGSDMVACEQCG 1369
            ....||   |..        |...|     |..:|.|    ||.::...:|....|:::..::.|
Mouse   189 HLRPPFLGMPTA--------VCQTPGFSFLPSAQAEMLARQQELLRKQSLARLEMSELLRQKELG 245

  Fly  1370 KM---------------EHKAKLKRK------RYCS-------------PG---------CSRQA 1391
            .:               |...:|:|:      ::.|             ||         .||..
Mouse   246 SVHRPLLPAPEVALHIPEGPDELQRRGSMLVLKHSSAPLLALPPQGPPGPGPPIPPKESARSRSE 310

  Fly  1392 KNGIGGVGS--GETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEA------TPK-------LS 1441
            |..:|...|  .||.|      .|:.|..:.:...:....|..:|.|      ||.       .:
Mouse   311 KGSLGVQPSQPKETTG------AGLWAQEVSEEPSKDSDGEDPETAAAREGTSTPSQVPAGGTRA 369

  Fly  1442 ESFPILGASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAPKSSEVNGTD 1506
            |...:|..||..||                :|||.|.....|.   ....|.|......|.  |.
Mouse   370 EGRGLLSGSTLPPP----------------LPLGFPCGAVSPY---FHTGTMGGLFTDEET--TT 413

  Fly  1507 RPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKV 1571
            ...::.|:||||.||:..|.||.:|...|.:|.|||:.|.||.|:||:|.||:||||||||.|:|
Mouse   414 LEDVNKWTVDDVCNFVGGLSGCGEYARVFGEQGIDGETLPLLTEEHLLNTMGLKLGPALKIRAQV 478

  Fly  1572 E--------------SIKEVPPPGEAKD--PGAQ 1589
            .              ::...||..:|.:  ||.|
Mouse   479 AKRLGRVFYMASFPVALPLQPPSLQAPELSPGHQ 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	SAM_Ph1,2,3	1508..1576	CDD:188976	35/81 (43%)
ph-p	NP_476871.2	SAM	1511..1576	CDD:197735	35/78 (45%)
Samd11	XP_006538909.1	SAM_Samd7,11	417..484	CDD:188978	35/66 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010