Protein Alignment ph-p and phc2

DIOPT Version :10

• Sequence 1: NP_476871.2
• Gene: ph-p / 31181
• FlyBaseID: FBgn0004861
• Length: 1589
• Species: Drosophila melanogaster
• Sequence 2: NP_001106410.2
• Gene: phc2 / 100127572
• XenbaseID: XB-GENE-996998
• Length: 804
• Species: Xenopus tropicalis
• Alignment Length: 902
• Identity: 219/902 - (24%)
• Similarity: 337/902 - (37%)
• Gaps: 246/902 - (27%)

  Fly   783 QKQQILQQQ-------QMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVN------AQQQQAV 834
            |..|::||.       |.|||..||   |||...:.:...|.|.:...|||.      .....|.
 Frog    40 QTVQVIQQHRPPSTAAQYLQQMYAA---QQQHLLLHSAALQHQHIQSLQQVGLATGRPGSAPAAT 101

  Fly   835 AQQQQA-----VAQAQQQQREQQQQVAQAQAQHQQA--LANATQQILQVAPNQFITSHQQQQQQQ 892
            ..||.:     :...|...|.|....|...|..|||  |.:||...|..:          |.|..
 Frog   102 VPQQSSPHSPGINSPQSISRPQSSTPAPPSAITQQAVLLGSATSPALSAS----------QAQMY 156

  Fly   893 LHNQLI---QQQLQQQAQAQVQA---------QVQAQAQQQQQQREQQQNIIQQIVVQQSGAT-- 943
            |..|::   ........|::|.|         ||.:.|.:.|......|:.:..:..:.:.:|
 Frog   157 LRAQMLIFTPTATVTSVQSEVSAGAPPPAGSTQVPSVAVRAQHSGLSPQSHLPSLARKPASSTLS 221

  Fly   944 SQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPT 1008
            :|..:...|...:|.|.|.|:|.:........|.:.::..:.|.|             |.:.:|.
 Frog   222 AQPVANAAQTKATGHLLLPSIPGAHLEPPDRKGESRAADGRGATS-------------CRTVAPV 273

  Fly  1009 SSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQGPPSLTPTTNPI 1073
            ::...|....:.||:           |....|:.|||.:|          ||:....|.....|:
 Frog   274 TAHSIIAPAHTHPLI-----------QQNHKQIQQHQFVI----------QPRAALPLPQLGAPL 317

  Fly  1074 LAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTA 1138
            ...|..           |.:..|:||..|||. .||                         ||.:
 Frog   318 QPFTHQ-----------PQLCQSLTSPPVTSQ-AQL-------------------------GPPS 345

  Fly  1139 TLVPI------GSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGA 1197
            |..|.      |.||....|::....|.|||......|...::.|.:.:|:    .|:.||...:
 Frog   346 TCAPQLHSAPGGPPKISPEGQERRLLPHSSTVILQLHSPPGTTPTPQDVSH----KRTFTPLGNS 406

  Fly  1198 ---------TTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVA 1253
                     |.|.:::|          .|...|..|...|..|.............||.:.:.:.
 Frog   407 PCLLHLHPPTAPLAQES----------APGGASVTETSDLCQCQPDDPRPPALPDPTIPSALDMT 461

  Fly  1254 RTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEA 1318
            ....|..|.|.:                   |.:|..||....|:|:::|.:|||||:||:|||.
 Frog   462 SGNGSAPVPTVA-------------------TGNSAQNGENKPPQAVVRPQILTHVIEGFVIQEG 507

  Fly  1319 NEPFPVTR-----------------QRYADKDVSDEPPKKKA--------TMQEDIKLSGIASAP 1358
            .:|||..|                 :||....::::.|::.:        :..|:..:.|...:.
 Frog   508 AQPFPSHRSRAAPEVGRSSLLIGAHERYPQGLLAEKVPQQDSNTTTTTTDSEMEETFVPGFPDSK 572

  Fly  1359 GS---DMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMAL 1419
            |.   ..:.||.||:::.:.|.|| ||:||..|:::.     .||..:..||
 Frog   573 GDGDPPKLKCELCGRVDFEYKFKRSKRFCSMACAKRY-----NVGCTKRVGL------------- 619

  Fly  1420 VDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQAAISAPSPLAMPLG--------- 1475
             ...|.:..::....:...:.::..|:...||: |...:|..|...||.|:..|..
 Frog   620 -FHPDRSKLQKPTGAKHARRRAQKGPLQSVSTD-PKKQVPASAPPIAPGPVPAPSALKHSNSQED 682

  Fly  1476 ----SPLSVALPTLAPLSVVTSGAAPKSSEVNGTDRPPISS-----------------WSVDDVS 1519
                |..|.....|:|||..:|.:.|: .|.|....||:.|                 |:|:||.
 Frog   683 SSRCSDNSSYEEPLSPLSASSSLSRPR-PERNLEAPPPLHSRDHIALNQDFLPSNPTKWNVEDVY 746

  Fly  1520 NFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKE 1576
            .|||.||||||..::|..|||||||||||||.||::||.:|||||||:.|::..:|:
 Frog   747 EFIRSLPGCQDISEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKLYARISMLKD 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	DUF5585	1015..>1232	CDD:465521	47/231 (20%)
		SAM_Ph1,2,3	1508..1576	CDD:188976	42/84 (50%)
phc2	NP_001106410.2	PHA03247	<27..457	CDD:223021	109/514 (21%)
		PHC2_SAM_assoc	610..735	CDD:465202	28/140 (20%)
		SAM_Ph1,2,3	735..803	CDD:188976	39/67 (58%)