DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG16903 and CCNL1

DIOPT Version :10

Sequence 1:NP_569980.1 Gene:CG16903 / 31178 FlyBaseID:FBgn0040394 Length:560 Species:Drosophila melanogaster
Sequence 2:NP_064703.1 Gene:CCNL1 / 57018 HGNCID:20569 Length:526 Species:Homo sapiens


Alignment Length:557 Identity:258/557 - (46%)
Similarity:325/557 - (58%) Gaps:85/557 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 SNNNSSSGAAPGADAAGGDAGGVAAAQADANKPIY--PRLFNRIVLTLENSLIPEGKIDVTPSSQ 103
            |...:::.|:..|.:|||.:.|...........|.  .||::.:.||:::|||||.::..|||.|
Human     7 STATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQ 71

  Fly   104 DGLDHETEKDLRILGCELIQTAGILLRLPQVAMATGQVLFQRFFYSKSFVRHNMETVAMSCVCLA 168
            ||||..:|.|||||||||||.|||||||||||||||||||.|||||||||:|:.|.|||:|:.||
Human    72 DGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLA 136

  Fly   169 SKIEEAPRRIRDVINVFHHIKQVRAQKEISPMVLDPYYTNLKMQVIKAERRVLKELGFCVHVKHP 233
            |||||||||||||||||||::|:|.::..||::||..|.|.|.||||||||||||||||||||||
Human   137 SKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHP 201

  Fly   234 HKLIVMYLQVLQYEKHEKLMQLSWNFMNDSLRTDVFMRYTPEAIACACIYLSARKLNIPLPNSPP 298
            ||:||||||||:.|:::.|:|.:||:|||||||:||:|:.||.||||||||:||.|.||||..|.
Human   202 HKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPH 266

  Fly   299 WFGIFRVPMADITDICYRVMELYMRSKPVVEKLEAAVDELKKRYIDARNKTKEANT--PPAVITV 361
            ||.:|.....:|.:||...:.||.|.||..|.||..|::.|....:|:.|.|..|.  .||:.|:
Human   267 WFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTL 331

  Fly   362 DRNNGSHNAWGGFIQRAIPLPLPS--------EKSP--------------------------QKD 392
                      |||    .|...||        ||||                          :||
Human   332 ----------GGF----SPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKD 382

  Fly   393 S-RSR-SRSRTRTHSRTPRSRSPRSRSPSRERTKKTHRSRSSRSRSRSPPKHKKKSRHYSRSPTR 455
            | ||| |||.:|:.||| |||| ||.:|.|....:..||.:..|||||      :||.:|.||.|
Human   383 SKRSRNSRSASRSRSRT-RSRS-RSHTPRRHYNNRRSRSGTYSSRSRS------RSRSHSESPRR 439

  Fly   456 SNSPHSKHRKSKSSRE------RSEYYSKKDRSGNPGSSNNLGDGDKYRNSVSNSGKHSRYSSSS 514
            .::..|.|.|:|.:|:      |..:..||.||.:...|.:..|..|.........:..|..|.|
Human   440 HHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRS 504

  Fly   515 SRRNSGGGGDGRSGGGGGGGGGGNGNHGSRGGH-KHR 550
            ..|:......|                |||.|| :||
Human   505 FERSHKSKHHG----------------GSRSGHGRHR 525

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16903NP_569980.1 CYCLIN_CCNL1_rpt1 104..227 CDD:410292 94/122 (77%)
CYCLIN_CCNL_rpt2 232..323 CDD:410236 53/90 (59%)
SDP_N <440..>482 CDD:463517 14/47 (30%)
CCNL1NP_064703.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..36 7/28 (25%)
CYCLIN_SF 40..195 CDD:477360 108/154 (70%)
Cyclin-like 1 88..190 77/101 (76%)
CYCLIN_SF 199..321 CDD:477360 65/121 (54%)
Cyclin-like 2 203..287 48/83 (58%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..526 74/246 (30%)
RS 390..432 22/49 (45%)

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