Protein Alignment CG4281 and GPATCH2

DIOPT Version :10

• Sequence 1: NP_569973.1
• Gene: CG4281 / 31171
• FlyBaseID: FBgn0025626
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_011507991.1
• Gene: GPATCH2 / 55105
• HGNCID: 25499
• Length: 551
• Species: Homo sapiens
• Alignment Length: 790
• Identity: 133/790 - (16%)
• Similarity: 215/790 - (27%)
• Gaps: 382/790 - (48%)

  Fly     1 MDQFSHDLTLALDLTLMDRASGGVGRWGSRRRTRS-------------------------TGNLP 40
            |::..|||..||:.: .::|.||....|...|:.|                         ||:
Human    25 MEELVHDLVSALEES-SEQARGGFAETGDHSRSISCPLKRQARKRRGRKRRSYNVHHPWETGH-- 86

  Fly    41 CAPQPTEDSSSSPTDALNQGHHHGHHGHHHHHHHTSANVDGLDTHNLKLPASDSDEKAEAMLPLR 105
            |..:.::.|...|:....:.|::....|                       ||||:  :.::..|
Human    87 CLSEGSDSSLEEPSKDYRENHNNNKKDH-----------------------SDSDD--QMLVAKR 126

  Fly   106 LPLTLPIRMGALESDSLN-----------ETTFSPARFYKPNSRRKRKIKRMSMEFEFSKDTSHT 159
            .|           |.:||           |:.|:.........||:||:|||:::.........|
Human   127 RP-----------SSNLNNNVRGKRPLWHESDFAVDNVGNRTLRRRRKVKRMAVDLPQDISNKRT 180

  Fly   160 FTESPLQPSLLSSSGSATGTIRKRLLKIDATGHRSHLFFCGKRKRSNRDRYHEQDSVKLYALPHS 224
            .|:.|                                       ...||:  :.||.:.|
Human   181 MTQPP---------------------------------------EGCRDQ--DMDSDRAY----- 199

  Fly   225 QVDDQHVEQPQHQQQRMRPRSYSSTSKPLSDRLLPLNKGLLSKINRMAAQGQQTKHTQKTETKDK 289
                      |:|:                                          ..|.:.|.:
Human   200 ----------QYQE------------------------------------------FTKNKVKKR 212

  Fly   290 DLKCHRSEGP----EGVSLEMEELPDQKDAVQKLPLPSADFTTANFNSISMDTIVPVTDIDALLL 350
            .||..| :||    |||.||.||
Human   213 KLKIIR-QGPKIQDEGVVLESEE------------------------------------------ 234

  Fly   351 STPPAAPLLRKKAQGQAPGHSSSSSSKTERRRRFQTFPQPQLQLQAQSMDCSE--LYDFL---SS 410
                                    :::|.:                ..|:|.|  :.|.|   |.
Human   235 ------------------------TNQTNK----------------DKMECEEQKVSDELMSESD 259

  Fly   411 SSLSSSTDSEAEVGGHRRHDTDREGDDELTDWPGNEFGPGARYDPKRKLTKKSLLPQIRSDDTIG 475
            ||..||||:     |...:|..|:||||.:||         .|:.:
Human   260 SSSLSSTDA-----GLFTNDEGRQGDDEQSDW---------FYEKE------------------- 291

  Fly   476 EDDTLMSGTEAGAVGMEP--PSKSPVQLPESLQD-------------LSRFQPAGVSEPIEIQNA 525
                  ||...|..|:.|  ..:.|.:|.:::.|             :|.....|....:...:.
Human   292 ------SGGACGITGVVPWWEKEDPTELDKNVPDPVFESILTGSFPLMSHPSRRGFQARLSRLHG 350

  Fly   526 CSEMETNADGTMPASRQIESEMSGETSNP-FLSSSP----------PG----HAQGQEVREIRAG 575
            .|.......|..|.|.   ..:.|...|. .:..||          ||    |.|.|.:|:.||.
Human   351 MSSKNIKKSGGTPTSM---VPIPGPVGNKRMVHFSPDSHHHDHWFSPGARTEHDQHQLLRDNRAE 412

  Fly   576 CRRINGERPGFSIKMSVNERIARFLQDSQQTQIRL-----PDIE-------LYETDSMSNLATLY 628
                .|.:...|::.:           |:||.:.|     .||:       |....:....:.:.
Human   413 ----RGHKKNCSVRTA-----------SRQTSMHLGSLCTGDIKRRRKAAPLPGPTTAGTCSHIL 462

  Fly   629 SLTMVVEHGCTVLTK---TGNTTQTVSMDHL------QQGLQPRADLFGDFKRRCYGEEGEEEGE 684
            ..|.|:.....:..|   .|...|.:..:::      ..|..|.:.|         |.:|:...|
Human   463 DETHVISLAIQIFHKAGFVGENAQPILENNIGNRMLQNMGWTPGSGL---------GRDGKGISE 518

  Fly   685 QQQPLQQDPG 694
            ..|.:|:..|
Human   519 PIQAMQRPKG 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4281	NP_569973.1	None
GPATCH2	XP_011507991.1	G-patch	491..532	CDD:396249	9/47 (19%)