Protein Alignment CG4313 and gpr25

DIOPT Version :10

• Sequence 1: NP_569971.3
• Gene: CG4313 / 31169
• FlyBaseID: FBgn0025632
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_073772858.1
• Gene: gpr25 / 795188
• ZFINID: ZDB-GENE-141216-12
• Length: 377
• Species: Danio rerio
• Alignment Length: 570
• Identity: 93/570 - (16%)
• Similarity: 174/570 - (30%)
• Gaps: 267/570 - (46%)

  Fly    15 IALPLSDPYATDH---MADQDAVLPVPLSDSLDLDVDVDLNLNMNLNLNVDDRRQVLFEGYSDEL 76
            |.:.|:..|..|:   ..|::.:..:|.::.|.:.           |:.:    .||:
Zfish    12 ITMSLTSEYDYDYPINSTDENPIYTLPDAELLPMS-----------NIYI----PVLY------- 54

  Fly    77 LTIAWVACIVFIIVGVPGNLLTIVALSRGRQTRNSTAI---FIINLSCSDLLFGCFNLPLAASTF 138
                    |:..:.|..|||..||.:  |::.:.|..:   |::||:.:||:| ...||:.|.:.
Zfish    55 --------IIMFLTGSLGNLFVIVVI--GKRRKKSGRLVDTFVLNLALADLVF-VLTLPMWAIST 108

  Fly   139 KERAWTHSDLLCRLFPMLRYGLLAVSLLS----VSLITINRYIIIAHPRQYPRIYQRRYL----- 194
            :...|...::||::...    ::||:..|    ::.::::||:.:.      |:...|:|
Zfish   109 RYDEWPFGEVLCKISSF----IIAVNRFSNIFFLTCMSVDRYLAVV------RLMDSRFLRSSNC 163

  Fly   195 ALMVAG-TWITTFSIMIPT--WRGVWGIFGLDVSIGSCSIMHDRYGRSPKEFL-------FIAAF 249
            |.:..| .|:.:|.:..|:  :|.:       ::...||  .|    |...|:       .:..|
Zfish   164 AQITCGIVWVVSFFLGSPSLAYRHL-------INNSVCS--ED----SKSSFVQGMNLLTILLTF 215

  Fly   250 MVPCICIVICYARIFLLVRKAAIRAGTAGKTNVSDVTPSSAPQHQIQAMATPKKPEKVTTSSGEA 314
            ::|.:.:.:||..|.:.:|:
Zfish   216 LLPVLILGLCYGSILVNLRR--------------------------------------------- 235

  Fly   315 NEPIAGRPFVVEENLAYIDDNASTDSLPISYSIRRRDQDQQPPPVDANVVLKEREKERDRDQEKV 379
                                                                             
Zfish   236 ----------------------------------------------------------------- 235

  Fly   380 SLGRSQTQLEMGKTHGKNPITTSLRTTSFTRFSPRKSHYASMGNTSNASSIYPGRMSAKDRRLLK 444
                          |..||..|                                |..|:.|..:|
Zfish   236 --------------HCHNPANT--------------------------------RTDARRRHSVK 254

  Fly   445 MILVIFVWFVICYLPITVAKIWKSATEVHWFNIAGYL-----------------LIYLTTCINPL 492
            ::..|...|:|.:||....|    |..|....|.|.|                 |.:|.:|:||.
Zfish   255 IVFAIISAFLISWLPFNCFK----AIHVALLIINGDLNEDTYVVIHRGLMLSCCLAFLNSCVNPA 315

  Fly   493 IYVLMSSEY-RRAYWNLLRCHGSPDTQKQRNQANAKRKHLESNRQVKATT 541
            ||..:...: |||....|.|      ..|.:||:  :.::.||.....|:
Zfish   316 IYFFLDQHFRRRASMLCLSC------LSQNDQAH--QSYITSNSYSNGTS 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4313	NP_569971.3	7tmA_GPR84-like	78..505	CDD:320338	74/466 (16%)
		TM helix 1	79..105	CDD:320338	7/25 (28%)
		TM helix 2	112..135	CDD:320338	8/25 (32%)
		TM helix 3	150..180	CDD:320338	6/33 (18%)
		TM helix 4	194..212	CDD:320338	5/23 (22%)
		TM helix 5	237..262	CDD:320338	6/31 (19%)
		TM helix 6	437..467	CDD:320338	9/29 (31%)
		TM helix 7	473..498	CDD:320338	10/41 (24%)
gpr25	XP_073772858.1	None