Protein Alignment CG4313 and Gpr88

DIOPT Version :10

• Sequence 1: NP_569971.3
• Gene: CG4313 / 31169
• FlyBaseID: FBgn0025632
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_071872.1
• Gene: Gpr88 / 64378
• MGIID: 1927653
• Length: 384
• Species: Mus musculus
• Alignment Length: 457
• Identity: 89/457 - (19%)
• Similarity: 140/457 - (30%)
• Gaps: 184/457 - (40%)

  Fly    89 IVGVPGNLLTIVALSRGRQTRNSTAIFIINLSCSDLLFGCFNLPLAASTFKERAWTHSDLLCRLF 153
            |.|...|.:.|..:|..|:.:.::..||:|        ||     ||.......|...:.:..|.
Mouse    43 IGGTLANGMVIYLVSSFRKLQTTSNAFIVN--------GC-----AADLSVCALWMPQEAVLGLL 94

  Fly   154 P------------------MLRYGL----LAVSLLSVSLITINRYIIIAH-PRQYPRIYQRRYLA 195
            |                  :||.||    |.|||||..|:.:|||::|.. |..|..:||||:..
Mouse    95 PSGSAEPPGDWDGGGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQVLYQRRHTV 159

  Fly   196 LMVAGTWITTFS--IMIPTWRGVWGIFGLDVSIGSCSIMHDRYGRSPKE-----FLFIAAFMVPC 253
            .|:|.:|.....  :::|.|.                   .:.|..|.:     .|...|.:...
Mouse   160 GMLALSWALALGLVLLLPPWA-------------------PKPGAEPPQVHYPALLAAGALLAQT 205

  Fly   254 ICIVICYARIFLLVRKAAIRAGTAGKTNVSDVTPSSAPQHQIQAMATPKKPEKVTTSSGEANEPI 318
            ..::.||..|...||.:..|........:..:...:|     .|.|.|..|.  ....|.|..|
Mouse   206 ALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAA-----AAAAFPAAPH--APGPGGAAHP- 262

  Fly   319 AGRPFVVEENLAYIDDNASTDSLPISYSIRRRDQDQQPPPVDANVVLKEREKERDRDQEKVSLGR 383
                                               .||.|:.|  .|:.|..:|
Mouse   263 -----------------------------------AQPQPLPA--ALQPRRAQR----------- 279

  Fly   384 SQTQLEMGKTHGKNPITTSLRTTSFTRFSPRKSHYASMGNTSNASSIYPGRMSAKDRRLLKMILV 448
                                                              |:|.     |.::|:
Mouse   280 --------------------------------------------------RLSG-----LSVLLL 289

  Fly   449 IFVWFVICYLPITVAKIWKS-----ATEVHW-FNIAGYLLIYLTTCINPLIYVLMSSEYRRAYWN 507
            ..| |::...|:    :|.|     :..|.| ...|.:||....:.:|||:|...:.|:||:..:
Mouse   290 CCV-FLLATQPL----VWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRS 349

  Fly   508 LL 509
            :|
Mouse   350 VL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4313	NP_569971.3	7tmA_GPR84-like	78..505	CDD:320338	88/451 (20%)
		TM helix 1	79..105	CDD:320338	5/15 (33%)
		TM helix 2	112..135	CDD:320338	5/22 (23%)
		TM helix 3	150..180	CDD:320338	16/51 (31%)
		TM helix 4	194..212	CDD:320338	3/19 (16%)
		TM helix 5	237..262	CDD:320338	6/29 (21%)
		TM helix 6	437..467	CDD:320338	5/29 (17%)
		TM helix 7	473..498	CDD:320338	8/25 (32%)
Gpr88	NP_071872.1	7tm_GPCRs	33..347	CDD:475119	88/451 (20%)
		TM helix 1	34..58	CDD:410628	4/14 (29%)
		TM helix 2	67..89	CDD:410628	8/34 (24%)
		TM helix 3	114..136	CDD:410628	11/21 (52%)
		TM helix 4	160..176	CDD:410628	3/15 (20%)
		TM helix 5	190..213	CDD:410628	3/22 (14%)
		TM helix 6	283..305	CDD:410628	6/31 (19%)
		TM helix 7	315..340	CDD:410628	8/24 (33%)