Protein Alignment CG4313 and aplnrb

DIOPT Version :10

• Sequence 1: NP_569971.3
• Gene: CG4313 / 31169
• FlyBaseID: FBgn0025632
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001025368.2
• Gene: aplnrb / 565492
• ZFINID: ZDB-GENE-050913-90
• Length: 359
• Species: Danio rerio
• Alignment Length: 482
• Identity: 83/482 - (17%)
• Similarity: 150/482 - (31%)
• Gaps: 197/482 - (40%)

  Fly    82 VACIVFIIVGVPGNLLTIVALSRGRQTRNSTAIFIINLSCSDLLFGCFNLPL-AASTFKERAWTH 145
            |..::..|:|:.||.:.|..:.|.:..|.:..::|.||:.:||.| ...||| |..|.....|..
Zfish    39 VLYMLIFILGLTGNGVVIFTVWRAQSKRRAADVYIGNLALADLTF-VVTLPLWAVYTALGYHWPF 102

  Fly   146 SDLLCRLFPMLRYGLLAVSLLSVSLITINRYIIIAHPRQYPRIYQRRYLALMVAGTWITTFSIMI 210
            ...||::...:....:..|:..::.::::||:.|.|.....::..|.::...:...|:.:..:..
Zfish   103 GVALCKISSYVVLLNMYASVFCLTCLSLDRYMAIVHSLTSTQLRTRGHMRASLTAIWLLSGVLAA 167

  Fly   211 PTWRGVWGIFGLDVSIGSCSIMHDRYGRSP-KEFLFIA---------AFMVPCICIVICYARIFL 265
            ||......::.::.:..||::..:.....| :|..:||         .|::|.:.:::||
Zfish   168 PTLLFRTTVYDVETNRTSCAMDFNLVVSQPGQETYWIAGLSISSTALGFLIPLLAMMVCY----- 227

  Fly   266 LVRKAAIRAGTAGKTNVSDVTPSSAPQHQIQAMATPKKPEKVTTSSGEANEPIAGRPFVVEENLA 330
                     |..|.|                          ||            |.|
Zfish   228 ---------GFIGCT--------------------------VT------------RHF------- 238

  Fly   331 YIDDNASTDSLPISYSIRRRDQDQQPPPVDANVVLKEREKERDRDQEKVSLGRSQTQLEMGKTHG 395
                          .|:|:.||
Zfish   239 --------------NSLRKEDQ------------------------------------------- 246

  Fly   396 KNPITTSLRTTSFTRFSPRKSHYASMGNTSNASSIYPGRMSAKDRRLLKMILVIFVWFVICYLPI 460
                                                      :.|||||:|..:.|.|..|::|.
Zfish   247 ------------------------------------------RKRRLLKIITTLVVVFAACWMPF 269

  Fly   461 TVAKIWKSATEVHWFNIA----------------GYLLIYLTTCINPLIYVLMSSEYRRAYWNLL 509
            .|.   |:...:.:.|:|                ...|.|:.:|:|||:|......:|.....||
Zfish   270 HVV---KTMDALSYLNLAPDSCTFLNLLLLAHPYATCLAYVNSCLNPLLYAFFDLRFRSQCLCLL 331

  Fly   510 R----CHGSP----DTQKQRNQANAKR 528
            .    .|.||    .:||...|:.|.:
Zfish   332 NLKKALHASPASSLSSQKTEAQSLATK 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4313	NP_569971.3	7tmA_GPR84-like	78..505	CDD:320338	74/449 (16%)
		TM helix 1	79..105	CDD:320338	6/22 (27%)
		TM helix 2	112..135	CDD:320338	9/23 (39%)
		TM helix 3	150..180	CDD:320338	4/29 (14%)
		TM helix 4	194..212	CDD:320338	1/17 (6%)
		TM helix 5	237..262	CDD:320338	8/34 (24%)
		TM helix 6	437..467	CDD:320338	11/29 (38%)
		TM helix 7	473..498	CDD:320338	9/40 (23%)
aplnrb	NP_001025368.2	7tmA_Apelin_R	25..327	CDD:341340	74/449 (16%)
		TM helix 1	36..62	CDD:341340	6/22 (27%)
		TM helix 2	69..94	CDD:341340	10/25 (40%)
		TM helix 3	107..137	CDD:341340	4/29 (14%)
		TM helix 4	150..171	CDD:341340	3/20 (15%)
		TM helix 5	204..233	CDD:341340	8/42 (19%)
		TM helix 6	246..276	CDD:341340	13/117 (11%)
		TM helix 7	295..320	CDD:341340	7/24 (29%)