Protein Alignment CG4313 and Mtnr1b

DIOPT Version :10

• Sequence 1: NP_569971.3
• Gene: CG4313 / 31169
• FlyBaseID: FBgn0025632
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001380770.1
• Gene: Mtnr1b / 192646
• RGDID: 620798
• Length: 364
• Species: Rattus norvegicus
• Alignment Length: 470
• Identity: 86/470 - (18%)
• Similarity: 146/470 - (31%)
• Gaps: 193/470 - (41%)

  Fly    81 WVA------CIVFIIVGVPGNLLTIVALSRGRQTRNSTAIFIINLSCSDLLFGCFNLPLAASTFK 139
            |||      .||...|...||||.|:::.|.|:.||:..:|::||:.:||:...:..||......
  Rat    38 WVAPMLSTVVIVTTAVDFVGNLLVILSVLRNRKLRNAGNLFVVNLALADLVVALYPYPLILVAIL 102

  Fly   140 ERAWTHSDLLCR--LFPMLRYGLLAV-SLLSVSLITINRYIIIAHPRQYPRIYQRRYLALMVAGT 201
            ...|...::.|:  .|.|   ||..: |:.:::.|.||||..|.|...|.|...:.:..|.::..
  Rat   103 HDGWVLGEIHCKASAFVM---GLSVIGSVFNITAIAINRYWCICHSATYHRACSQWHAPLYISLI 164

  Fly   202 WITTFSIMIPTWRGVWGIFGLDVSIGSCSIMHDRYGRSPKEFLFIAA--FMVPCICIVICYARIF 264
            |:.|...::|.:  ..|....|..|.||:.:..   .|.:..:.:.|  |::|...:..||.||:
  Rat   165 WLLTLVALVPNF--FVGSLEYDPRIYSCTFIQT---ASTQYTMAVVAIHFLLPIAVVSFCYLRIW 224

  Fly   265 LLVRKAAIRAGTAGKTNVSDVTPSSAPQHQIQAMATPKKPEKVTTSSGEANEPIAGRPFVVEENL 329
            :||                           :||....|...|:
  Rat   225 ILV---------------------------LQARRKAKAERKL---------------------- 240

  Fly   330 AYIDDNASTDSLPISYSIRRRDQDQQPPPVDANVVLKEREKERDRDQEKVSLGRSQTQLEMGKTH 394
                                                                             
  Rat   241 ----------------------------------------------------------------- 240

  Fly   395 GKNPITTSLRTTSFTRFSPRKSHYASMGNTSNASSIYPGRMSAKDRRLLKMILVIFVWFVICYLP 459
                                                   |:...|.|....:..:||.|.||:.|
  Rat   241 ---------------------------------------RLRPSDLRSFLTMFAVFVVFAICWAP 266

  Fly   460 ITVAKIWKS------ATEV-HWFNIAGYLLIYLTTCINPLIYVLMSSEYRRAYWNLL-------- 509
            :....:..:      |.:: ....:..|.|.|..:|:|.::|.|::..:||.|..:|
  Rat   267 LNCIGLAVAINPEAMALQIPEGLFVTSYFLAYFNSCLNAIVYGLLNQNFRREYKRILSALWSTGR 331

  Fly   510 ------RCHGSPDTQ 518
                  :||.:.|.|
  Rat   332 CFHDASKCHLTEDLQ 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4313	NP_569971.3	7tmA_GPR84-like	78..505	CDD:320338	80/441 (18%)
		TM helix 1	79..105	CDD:320338	11/29 (38%)
		TM helix 2	112..135	CDD:320338	7/22 (32%)
		TM helix 3	150..180	CDD:320338	11/32 (34%)
		TM helix 4	194..212	CDD:320338	3/17 (18%)
		TM helix 5	237..262	CDD:320338	6/26 (23%)
		TM helix 6	437..467	CDD:320338	8/29 (28%)
		TM helix 7	473..498	CDD:320338	7/24 (29%)
Mtnr1b	NP_001380770.1	7tm_GPCRs	41..319	CDD:475119	77/438 (18%)
		TM helix 1	43..67	CDD:410628	8/23 (35%)
		TM helix 2	76..98	CDD:410628	7/21 (33%)
		TM helix 3	114..136	CDD:410628	6/24 (25%)
		TM helix 4	159..175	CDD:410628	3/15 (20%)
		TM helix 5	198..221	CDD:410628	4/22 (18%)
		TM helix 6	250..272	CDD:410628	6/21 (29%)
		TM helix 7	287..312	CDD:410628	7/24 (29%)