Protein Alignment usp and nr2e3

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001007369.2
• Gene: nr2e3 / 492496
• ZFINID: ZDB-GENE-041114-63
• Length: 426
• Species: Danio rerio
• Alignment Length: 495
• Identity: 152/495 - (30%)
• Similarity: 223/495 - (45%)
• Gaps: 108/495 - (21%)

  Fly    39 ESPVPFMQAMSMVHVLPGSNSASSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHL 103
            |.|   |..||||..  .|.:.||.:||..|:|..::|               .|...|: :..|
Zfish     2 EDP---MSEMSMVPF--SSPTESSRSNSTDDSQDGKSP---------------APGKVLN-TGLL 45

  Fly   104 CSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRN-CIIDKRQRNRCQYCRYQKCLTC 167
            |.:|.|.:||||||:|:|.||.|||||:||:.|.|.|:.... |.:||..||:||.||.:|||..
Zfish    46 CKVCSDTSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQAGTGMCPVDKAHRNQCQACRLKKCLQA 110

  Fly   168 GMKREAVQEERQRGARNAAGRLSASG-------------GGSSGPGSVGGSSSQGGGGGGGVSGG 219
            ||.::|||.|||..: .|..||.|..             ..||...||......|......:|..
Zfish   111 GMNKDAVQNERQPRS-TAQVRLDALDVDKDKEHLATTLEPTSSSTCSVISRPLLGSSISSSISST 174

  Fly   220 MGSGNGSDD-----FMTNSVSR-----------DFSIERIIEAEQRAETQCGDRALTFLRVGPYS 268
            .||.:.:..     ||.:.::.           |.:|:......:|:....|. ||       |.
Zfish   175 DGSQHSNSPKNGHRFMASLMTAETCAKLEPEDVDENIDVTSNEPERSSPMYGS-AL-------YP 231

  Fly   269 TVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIEL-LIANVAW---- 328
            :.:|:.....||      :.||..|::|:.:|.|:.:|..||||||:.||.|| |:..:.|
Zfish   232 SREPESVYETSA------RLLFMSVKWAKNLPVFSHLPFRDQVILLEEAWSELFLLCAIQWSLPL 290

  Fly   329 --CSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILS 391
              |.::||.|....|.|.|          ||                         ||...|:|.
Zfish   291 DNCPLLSLPDLSPTGQGKG----------SP-------------------------SASDVRVLQ 320

  Fly   392 ELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFA 456
            |:..:.|.|.:|..|.:|||||:|:.|:.||:|...::|..:::....|.:|....:|....||.
Zfish   321 EVFSRFKPLQVDPTEFACLKAIVLFKPETRGLKDPEQVENLQDQSQVLLAQHIHTLYPSQVARFG 385

  Fly   457 QLLLRLPALRSISLKCQDHLFLFRITSDRPLEELFLEQLE 496
            :|||.||:|..:|.:..:|||..|...:.|:|:|..:..:
Zfish   386 RLLLLLPSLHFVSSERIEHLFFQRTIGNTPMEKLLCDMFK 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	41/76 (54%)
		NR_LBD_RXR_like	237..480	CDD:132741	73/249 (29%)
nr2e3	NP_001007369.2	NR_DBD_PNR	38..129	CDD:143528	46/92 (50%)
		NR_LBD_Tlx_PNR_like	208..413	CDD:132748	74/253 (29%)