Protein Alignment usp and nhr-154

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_506037.2
• Gene: nhr-154 / 182565
• WormBaseID: WBGene00007547
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 260
• Identity: 47/260 - (18%)
• Similarity: 101/260 - (38%)
• Gaps: 88/260 - (33%)

  Fly   985 ISNVREYP---KEP--MIDKCT---------IRDSWPDDGKIE--IKNLNVFANKYRHVIKDVSL 1033
            :.::.|:|   .:|  :.|:.|         :::|..:...|:  |||    |:..:..:|||:.
 Worm    46 VKSIAEFPFSTSKPHDVHDEATPITEITTLPVQESIKNSDPIQESIKN----ADSVQDSVKDVAE 106

  Fly  1034 VIEEREKLGIIGKVGSGKSQLAKTLVMMSSADKESHIVV--DDLDIF---------------EMS 1081
            .::|.          ..|::..|.:.:.::.:.|..:.:  ::.|:|               |..
 Worm   107 PVQEE----------VSKTEEVKKIELFAATEDEEDVELPPEECDLFTGEWVFDNETHPLYKEDQ 161

  Fly  1082 VKTLRSRITVIPQKAKIFSDTLRSNIDPCCQFADSDIWLAIEACQLREYVKSLPDGLHQMVSPEK 1146
            .:.|.:::|.:....:   |:|..|            |    ..|.|:.  |||....:::. ||
 Worm   162 CEFLTAQVTCMRNGRR---DSLYQN------------W----RWQPRDC--SLPKFKAKLLL-EK 204

  Fly  1147 MSNEQKCQVNVCRALLKGGQIFVIDQSTKMMKEPIKSLVNEAI---RNSLKQ--STTIWIGEDFS 1206
            :.|::              .:||.|...:...|.:..||...:   |.||.:  |.:::..||::
 Worm   205 LRNKR--------------MMFVGDSLNRNQWESMVCLVQSVVPPGRKSLNKTGSLSVFRVEDYN 255

  Fly  1207  1206
             Worm   256  255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514
		NR_LBD_RXR_like	237..480	CDD:132741
nhr-154	NP_506037.2	NR_DBD_HNF4A	83..160	CDD:143518	14/90 (16%)
		HOLI	266..429	CDD:214658