Protein Alignment usp and nhr-148

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_504871.1
• Gene: nhr-148 / 182172
• WormBaseID: WBGene00015396
• Length: 370
• Species: Caenorhabditis elegans
• Alignment Length: 432
• Identity: 100/432 - (23%)
• Similarity: 150/432 - (34%)
• Gaps: 115/432 - (26%)

  Fly   104 CSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRN----RCQYCRYQKC 164
            ||||...|.|.||.|.||:|||.||:|....:....|..|..| .|..:.|    ||:.|||:||
 Worm    11 CSICRRNAKGYHYDVISCKGCKTFFRRMSLINFQGKCDLNNQC-FDLTKANEPYLRCRACRYRKC 74

  Fly   165 LTCGMKREAVQ-EERQRG-------ARNAAG------------RLSASGGGSSGPGSVGGSSSQ- 208
            |..||.::|:| .||.:.       .:|...            ||||     ..|.....|..:
 Worm    75 LDVGMNQKAIQIPERNQTFGVIETMTKNTIDALVYLEEKLEKFRLSA-----DNPHWQAVSDLEL 134

  Fly   209 --GGGGGGGVSGGMGSGNGSDDFMTNSVSRDF----SIERIIEAEQRAE-TQCGDRALTFLRVGP 266
              ..|...|::...|      ....|||...|    |:...::|.|..: ..|
 Worm   135 YLNNGSNLGLADKFG------PTFENSVHESFEPKNSLPSSLKAVQNNKLNHC------------ 181

  Fly   267 YSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSI 331
                 |..|  :..||     .|...|||.:...:|..:...|::||.:..   :||......|
 Worm   182 -----PTKK--IWTLC-----NLLTTVEYLKTFNYFKDLSALDKLILARHV---ILIGKNLHIS- 230

  Fly   332 VSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDR---ILSEL 393
                                               |.|||......:.....|..:|   :...|
 Worm   231 -----------------------------------NYSFSKKFTGCLNIETDAQRERHYPVAFML 260

  Fly   394 SVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREK--VYACLDEHCRLEHPGDDGRFA 456
            ...:.|..:...|...||||...||.:..:..:|:..:.||:  ..:.|.::|:.......||||
 Worm   261 MAPLIRSQIQPIEYILLKAICCCNPAVPNLSQKAQSTLARERGQFVSILFDYCQRSGKNGPGRFA 325

  Fly   457 QLLLRLPALRSISLKCQDHLFLF---RITSDRPLEELFLEQL 495
            :|:.....:.......:|...|:   .:|.|..::..||..:
 Worm   326 ELIGIFSVMEKQQRMQKDMYMLYFAPHLTPDVKIQIKFLHDI 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	34/78 (44%)
		NR_LBD_RXR_like	237..480	CDD:132741	47/255 (18%)
nhr-148	NP_504871.1	ZnF_C4	10..80	CDD:197701	31/69 (45%)
		HOLI	191..337	CDD:214658	36/184 (20%)