Protein Alignment Edem1 and Edem1

DIOPT Version :10

• Sequence 1: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_619618.1
• Gene: Edem1 / 192193
• MGIID: 2180139
• Length: 652
• Species: Mus musculus
• Alignment Length: 602
• Identity: 230/602 - (38%)
• Similarity: 319/602 - (52%)
• Gaps: 112/602 - (18%)

  Fly     1 MQQKPRNNGYPGTLICAVLLVLLSTGVSG------QKQYSKA----RKLELREDVRRMFQHAYDG 55
            ::..|.....||..:|.......:.|..|      :::||.|    .:.::|:..|.||...||.
Mouse    75 LETPPEPGPTPGPGVCGPAHWGYALGGGGCGPDEYERRYSGAFPPQLRAQMRDLARGMFVFGYDN 139

  Fly    56 YLRHASNYDELRPLTCDG-------------HDTWGSYSLTLIDALDTLATMGNFTEFRRAARLL 107
            |:.||...|||.|:.|.|             :|..|:|||||:|||||||.|||.:||::|.:|:
Mouse   140 YMAHAFPQDELNPIYCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLV 204

  Fly   108 EEKMDFDRDINVSVFETNIRIVGGLLSAHLL---SKR--AGVELEPGWPCKGPLLRLAEDVARRL 167
            ...:.||:|..|.|||..||::|.|||||.:   ||:  ..:.:|   .....||.:|.|:|.||
Mouse   205 INTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIE---DYDNELLYMAHDLAVRL 266

  Fly   168 LPAFV-TNTGMPYGTVNLRYGVPKGETSITCTAGVGTFLIEFGTLSRLTGKTIYEDVAMKAVHAL 231
            ||||. |.||:||..|||:.|||....:.|||||.|:.|:|||.||||.|.:.:|.||.:||.||
Mouse   267 LPAFENTKTGIPYPRVNLKTGVPPDSNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKAL 331

  Fly   232 WAYRS-PIGLFGNHIDVQSGRWTALDSGIGAGVDSLFEYLVKASVLLNRPELLELFHEARAAIDK 295
            |..|| ..||.||.:::|:|.|....||:|||:||.:|||:|:.:|....|.||:|:.|..:|..
Mouse   332 WNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQS 396

  Fly   296 YMRK-----------EDWYVWVGMNKGRVTLPVFQSLEAFWPGILSIIGDTEPALRTISRYIGVW 349
            |:|:           ...||.|.|..|::......||:||:||:..:|||.|.|:...:.|..:|
Mouse   397 YLRRGREACNEGEGDPPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIW 461

  Fly   350 KKYGFLPEFYNIAAGEASPNREVYPLRPELIESAMYLYRATGNEYLLEFGEHMLETLEFSAKTKC 414
            |:||.|||.||...  .:|:...|||||||:||...||:||.|.:.|..|..:|::||...|.||
Mouse   462 KRYGALPERYNWQL--QAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKC 524

  Fly   415 GYATIRNVVTHEKENRMESFFLAETSKYLYLLFDEENFLHNDGSGGELLSTEDDVCVVQAGAYIF 479
            ||||:.:|:...||:|||||||:||.|||||||||||.:|..|:                 .|:|
Mouse   525 GYATLHHVIDKSKEDRMESFFLSETCKYLYLLFDEENPVHKSGT-----------------RYMF 572

  Fly   480 NTEAHPMDMSALHCCHAHNEDIYTSLDLQRFSPRAILERSKKRQVAVQEQWVPQCHPENNEFFNK 544
            .||.|                              |:...|:.:   :..|        .|||
Mouse   573 TTEGH------------------------------IISVDKRLR---ELPW--------KEFF-- 594

  Fly   545 EDESVQAQDSEKEQERE 561
                  ::|.|::||.:
Mouse   595 ------SEDGERDQEEK 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:460241	209/468 (45%)
Edem1	NP_619618.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..86		1/10 (10%)
		Glyco_hydro_47	132..577	CDD:460241	204/475 (43%)