Protein Alignment Edem1 and mans-2

DIOPT Version :10

• Sequence 1: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001256389.1
• Gene: mans-2 / 179642
• WormBaseID: WBGene00008258
• Length: 590
• Species: Caenorhabditis elegans
• Alignment Length: 482
• Identity: 140/482 - (29%)
• Similarity: 229/482 - (47%)
• Gaps: 73/482 - (15%)

  Fly    42 REDVRRMFQHAYDGYLRHASNYDELRPLT--CDGHDTWGSYSL--TLIDALDTLATMGNFTEFRR 102
            |:.|:.|..||::||..::...:||||::  .:..:.:|...:  |::||.|||..|....:::.
 Worm   140 RQKVKEMMIHAWEGYKNYSWGANELRPMSKKPNSQNIFGGSQMPATIVDAADTLFIMDLKDKYKE 204

  Fly   103 AARLLEEKMDFDRDIN-VSVFETNIRIVGGLLSAHLLSKRAGVELEPGWPCKGPLLRLAEDVARR 166
            |...:|......:..: :|||||.||.:|||||.:.|::.:.            .:..|.:|...
 Worm   205 ARDYIENNFSMAKSTSTLSVFETTIRFLGGLLSLYALTQESF------------YIEKAREVGEA 257

  Fly   167 LLPAFVTNTGMPYGTVNL------RYGVPKGETSITCTAGVGTFLIEFGTLSRLTGKTIYEDVAM 225
            |||||.|.:|:|...:::      .||...|..||  .:.:|:..:||..|||::...|:|....
 Worm   258 LLPAFNTPSGIPKSNLDVASKHASNYGWANGGQSI--LSEIGSLHLEFLYLSRISNAPIFEKKVK 320

  Fly   226 KAVHALWAYRSPIGLFGNHIDVQSGRWTALDSGIGAGVDSLFEYLVKASVLLN--RPELLELFHE 288
            |...||.....|.||:.|:|:..:|::|.....:||..||.:|||:|:.|..|  ..:...::.:
 Worm   321 KVRDALEKAEKPNGLYSNYINPDTGKFTGSHMSLGALGDSFYEYLIKSYVQSNYTDTQAKNMYWD 385

  Fly   289 ARAAIDKYM----RKEDWYVWVGMNKGRVTLPVFQSLEAFWPGIL---SIIGDT-EPALRTIS-- 343
            ...||.|:|    ::.:....|.:|.|:....: ..|..|.||:.   :|..|| |..||.::
 Worm   386 VSDAIQKHMIKVSKQSNLTYTVELNNGQAQHKM-GHLACFVPGMFALQAINEDTEEEKLRIMTLA 449

  Fly   344 ---------RYIGVWKKYGFLPE-FYNIAAGEASP--NREVYPLRPELIESAMYLYRATGNEYLL 396
                     .||......|  || ||.....||:.  :...|..|||:||...||:|.||.....
 Worm   450 EELAKTCHESYIRSETHIG--PEMFYFNERDEATSKHSENGYIQRPEVIEGWFYLWRLTGKTMYR 512

  Fly   397 EFGEHMLETLEFSAKTKCGYATIRNVVTHE--KENRMESFFLAETSKYLYLLFDEENFLHNDGSG 459
            ::....::.:|...:...|:..::||...:  :|:.|:||||||..||.||.|.:|:.:..|
 Worm   513 DWVWDAVQAIEKYCRVDSGFTGLQNVYNPKAGREDVMQSFFLAEFLKYAYLTFADESLISLD--- 574

  Fly   460 GELLSTEDDVCVVQAGAYIFNTEAHPM 486
                            .::|||||||:
 Worm   575 ----------------KWVFNTEAHPV 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:460241	137/474 (29%)
mans-2	NP_001256389.1	LanC_like	103..587	CDD:471159	140/482 (29%)