DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL16 and MRPL16

DIOPT Version :9

Sequence 1:	NP_001259148.1	Gene:	mRpL16 / 31150	FlyBaseID:	FBgn0023519	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_060310.1	Gene:	MRPL16 / 54948	HGNCID:	14476	Length:	251	Species:	Homo sapiens

Alignment Length:	221	Identity:	113/221 - (51%)
Similarity:	149/221 - (67%)	Gaps:	7/221 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 TAGLKYFAPPIKYQNVEQPERPKLRVIERQPQLPPNIRPPKMQKRLRYMRGPEMVHNTLLHKQYA 89
            :||:|...|...:::|..||:||||.|||.|.:|...|.|   |.|..:|||...........:|
Human    27 SAGVKTLLPVPSFEDVSIPEKPKLRFIERAPLVPKVRREP---KNLSDIRGPSTEATEFTEGNFA 88

  Fly    90 IVATGGGRLRWGHYEMMRLTIGRKMNVNTMFATWRVPAPWQPITKKGQGQRMGGGKGAIDHYVTP 154
            |:|.|||.|.|||:|||||||.|.|:...|||.||||||::|||:|..|.|||||||||||||||
Human    89 ILALGGGYLHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTP 153

  Fly   155 IKAGRVIVEIAGKCEFVEVKQFLQQVANQLPFQATVVSQEMLDEQRVAEEEQTRQNENPFTMKYV 219
            :||||::||:.|:|||.||:.||.|||::|||.|..||:..|::.|..:||:.|.|:||:|.:.:
Human   154 VKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERI 218

  Fly   220 IQNNLSGCHRWLSPVD--H--KWFGK 241
            ...|:.|..:.|||.|  |  |::||
Human   219 ATANMLGIRKVLSPYDLTHKGKYWGK 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL16	NP_001259148.1	Ribosomal_L16	64..184	CDD:278672	71/119 (60%)
MRPL16	NP_060310.1	Ribosomal_L16	60..190	CDD:395194	77/132 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147771
Domainoid	1	1.000	160	1.000	Domainoid score	I4074
eggNOG	1	0.900	-	-		E1_COG0197
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9872
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3551
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45726
OrthoDB	1	1.010	-	-		D1420525at2759
OrthoFinder	1	1.000	-	-		FOG0002930
OrthoInspector	1	1.000	-	-		oto90204
orthoMCL	1	0.900	-	-		OOG6_101573
Panther	1	1.100	-	-	LDO	PTHR12220
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5004
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770