Protein Alignment dor and AT1G12470

DIOPT Version :10

• Sequence 1: NP_477286.2
• Gene: dor / 31118
• FlyBaseID: FBgn0000482
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_172709.2
• Gene: AT1G12470 / 837804
• AraportID: AT1G12470
• Length: 988
• Species: Arabidopsis thaliana
• Alignment Length: 1040
• Identity: 283/1040 - (27%)
• Similarity: 475/1040 - (45%)
• Gaps: 198/1040 - (19%)

  Fly    61 DLMHLAVSRNWLVCLLGTPERTTLLRFFLPRAIPPGEAVLEKYLSGSG--------------YKI 111
            |::.|..|:.|::                            :|..|.|              ..|
plant    32 DVIVLGTSKGWII----------------------------RYDFGVGSSNDIDLAVGRTGEQSI 68

  Fly   112 TRMFLDPTGHHIIIALVPKSATAGV-SPDFLYIHCLESPQAQQLKVRRIEKFKDHEITAVAFNPY 175
            .::|:||.|.|.|      :...|| ..:..|.|      |:.||.|.:.:.|...:.|||:|..
plant    69 HKVFVDPGGSHCI------ATVTGVGGAETFYTH------AKWLKPRVLSRLKGLLVNAVAWNRQ 121

  Fly   176 HGNESSTGPILLGTSRGLIFETELNPAADGHVQRKQLYDLGLGRPKYPITGLKLLRVPNSSRYII 240
            ...|.||..|:|||..|.:||..::.........|.|::|......:....::...:.:..||.:
plant   122 QITEVSTKEIILGTQDGQLFEMAVDEKDKREKYIKFLFELEELPEAFKALQMETANISSGMRYYV 186

  Fly   241 VVTSPECIYTFQETLKAEERSLQAIFAGYVSGVQEPHCEERKTDLTFSQLRFFAPPNSKYPKQWA 305
            :..:|..:|:|...     .:|:::||.|..  :..|..|...::..|:|.||.  ..:....:|
plant   187 MAVTPTRLYSFTGI-----GTLESVFASYKE--RAVHFMELPGEIPNSELHFFI--KQRRAVHFA 242

  Fly   306 WLCGEGIRVGELSIEA-----NSAATLIGNTLINLDFEKTMHLSYGERRLNTPKAFVLTEYHAVL 365
            ||.|.||..|.|:..|     |.....:.|..: ||:.|   ||.|...:. |.:..|:|||.:|
plant   243 WLSGTGIYHGGLNFGAQHSYPNGDENFVENKAL-LDYSK---LSDGTEAVK-PGSMALSEYHFLL 302

  Fly   366 LYADHVRAICLLNQEQVYQEAFDEARVGKPLSIERDELTGSI------------YVYTVKTVFNL 418
            |..:.|:.:..::::.:.:..||         |..|.::..|            |.|...::|.:
plant   303 LIGNKVKVVNRISEQIIEELQFD---------ITSDSVSRGIIGLCSDASANVFYAYDQNSIFQV 358

  Fly   419 RVTREERNVWRIYLDKGQYELATAHAAEDPEHLQLVLCQRADAAFADGSYQVAADYYAETDK--S 481
            .|..|.|::|::|||...|..|.|:..:..:..|:.|.| |::||.|..|..||.:||:.:.  |
plant   359 SVIDEGRDMWKVYLDLKVYAAALANCRDPLQRDQVYLVQ-AESAFTDKEYLRAASFYAKINYVIS 422

  Fly   482 FEEVCLKFMVLPDKRPIINYVKKRLSRVTTKPMETDELDEDKMNIIKALVIWLIDLYLIQIN--- 543
            ||||.|||:.:.:...:..::..:|          |.|.:|....|..:..|..:|||.:||
plant   423 FEEVTLKFISINEPEALRTFLLHKL----------DNLSKDDKCQITMISTWATELYLDKINRLL 477

  Fly   544 ------MPDKDEEWRSSWQTEYDEFMMEAHVLSCTRQ-NRETVRQLIAEHADPRNMAQFAIAIGD 601
                  :.::|.|:.|..| |:..||.:     |..: :..|..:::..:.....:..||.....
plant   478 LEDDTAIENRDSEYHSVIQ-EFRAFMSD-----CKDELDEATTVKILESYGRVEELVYFANLKEQ 536

  Fly   602 YDEVV---AQQLKAECYAEALQTLINQRNPELFYKYAPELITRLPKPTVDALMAQGSRLEVEKLV 663
            |:.||   .||.:|:...|.||.  :..:.||.|::|||||......||::.|| ...|...:|:
plant   537 YEIVVLHYIQQGEAKKALEVLQK--SSVSVELQYQFAPELIMLDAYETVESWMA-NKNLNPRRLI 598

  Fly   664 PTLIIMEN----REQREQTQRYLEFAIYKLNTTNDAIHNFLLHLYAEHEPK-LLMKYLEI---QG 720
            ..::...:    :.:..:..:||||.:::|:..:..||:.||.|||:.|.. .|:::|:.   :|
plant   599 TAMMRYSSGPHAKNETHEVIKYLEFCVHRLHNEDPGIHSLLLSLYAKQEDDGALLRFLQCKFGKG 663

  Fly   721 RDES-LVHYDIYYAHKVCTDLDVKEAR----VFLECMLRKWISAVDLALTFDMKLAKETASRPSD 780
            |:.. ...||..||.::|    :||.|    |.:..|:.....||.|||..|.:||...|.:..|
plant   664 RENGPEFFYDPKYALRLC----LKERRTRACVHIYSMMSMHEEAVALALQIDPELAMAEADKVED 724

  Fly   781 SK-IRRKLWLRIAYHDIK-----GTNDVKKALNLLKECD-LLRIEDLLPFFADFEKIDNFKEAIC 838
            .: :|:||||.:|.|.:|     ...:::||:..|||.| ||:|||:||||.||..||:||||||
plant   725 DEDLRKKLWLMVAKHVVKQEKGAKRENIRKAIAFLKETDGLLKIEDILPFFPDFALIDDFKEAIC 789

  Fly   839 DALRDYNQRIQELQREMAETTEQTDRVTAELQQLRQHSLTVESQDTCEICEMMLL---------- 893
            .:|.|||::|::|:.||.:.|...|.:..::..|.|....::..:.|.:|:..:|
plant   790 SSLEDYNKQIEQLKEEMNDATRGADNIRNDISALTQRYAVIDRDEECGVCKRKILMMSGDFRMAQ 854

  Fly   894 -------VKPFFIFICGHKFHSDCLEKHVVPLLTKEQCRRLGTLKQQLEAEVQTQAQPQSGALSK 951
                   :.||::|.|||.||:.||..||.....:||...:..|::||.            .|..
plant   855 GYSSAGPLAPFYVFPCGHSFHAQCLITHVTSCAHEEQAEHILDLQKQLT------------LLGS 907

  Fly   952 QQAMELQRKRA-----------ALKTEIEDILAADCLFCG-LLISTIDQPFV--DDWEQVNVEWE 1002
            :...::...|:           .|::|::|.:|::|.||| |:|:.|..||:  :| .|.:..|:
plant   908 ETRRDINGNRSDEPITSTTTADKLRSELDDAIASECPFCGELMINEITLPFIKPED-SQYSTSWD 971

  Fly  1003  1002
            plant   972  971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dor	NP_477286.2	Pep3_Vps18	311..464	CDD:461557	44/169 (26%)
		Clathrin	650..783	CDD:459884	41/146 (28%)
		RING_Ubox	883..981	CDD:473075	30/126 (24%)
AT1G12470	NP_172709.2	Pep3_Vps18	248..402	CDD:461557	43/168 (26%)
		Clathrin	592..745	CDD:459884	47/156 (30%)
		RING_Ubox	834..951	CDD:473075	31/128 (24%)