DRSC/TRiP Functional Genomics Resources

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Protein Alignment sta and RPSA2

DIOPT Version :10

Sequence 1:NP_476750.1 Gene:sta / 31106 FlyBaseID:FBgn0003517 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_001342212.1 Gene:RPSA2 / 388524 HGNCID:36809 Length:295 Species:Homo sapiens


Alignment Length:282 Identity:171/282 - (60%)
Similarity:200/282 - (70%) Gaps:20/282 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNILNLGKTWEKLQLAARAI 65
            |||.||:|.:||:|:.|.|.|.||||..|::||||.|:|||::||:.|:||.:|||||.||||||
Human     1 MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEHYIYKRKSDGIYIINLKRTWEKLLLAARAI 65

  Fly    66 VAIDNPSDIFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPNTD 130
            |||:||:|:.|||||..|||||||||..|..||||||||||.||||||.||.||||||||||..|
Human    66 VAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFWEPRLLVVTDPRAD 130

  Fly   131 HQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRGTISRSVEW 195
            |||:.||||||:|.||..||||||||:|||||||||.|||:|||||:|||||||:||||||...|
Human   131 HQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPW 195

  Fly   196 PVVVDLFFYRDPEEAEKEEAAAKE------------LLPPPKIEEAVDHPVEETTNWADEVAAET 248
            .|:.||:|||||||.||||.||.|            ..|.|  |.....|  |..:|::.|...:
Human   196 EVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPSP--EFTATQP--EVADWSEGVQVPS 256

  Fly   249 VG----GVEDWNEDTVKTSWGS 266
            |.    ..|||:.......|.:
Human   257 VPIQQFPTEDWSAQPATEDWSA 278

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
staNP_476750.1 PTZ00254 1..247 CDD:240331 166/257 (65%)
RPSA2NP_001342212.1 PTZ00254 1..250 CDD:240331 165/252 (65%)
Interaction with PPP1R16B. /evidence=ECO:0000255|HAMAP-Rule:MF_03016 54..113 46/58 (79%)
Laminin-binding. /evidence=ECO:0000255|HAMAP-Rule:MF_03016 161..180 15/18 (83%)
Laminin-binding. /evidence=ECO:0000255|HAMAP-Rule:MF_03016 205..229 12/23 (52%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 218..242 4/25 (16%)
Laminin-binding. /evidence=ECO:0000255|HAMAP-Rule:MF_03016 242..295 9/39 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 266..295 3/13 (23%)

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