Protein Alignment CG14780 and KLK6

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 83/259 - (32%)
• Similarity: 116/259 - (44%)
• Gaps: 34/259 - (13%)

  Fly    17 LLACAAADLQENQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGH-ICGGALIAPRKVLTAAH 80
            |:|.|.|:    :|:::::|  ...|:|.|.....|      :.||| :|||.||.|..||||||
Human    10 LIAAAWAE----EQNKLVHG--GPCDKTSHPYQAAL------YTSGHLLCGGVLIHPLWVLTAAH 62

  Fly    81 CLYNNQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSP--DSMRDDVGILFLRTG 143
            |...|.:          |.||..|..:..:    ||..|........|  |:...|..|:.||..
Human    63 CKKPNLQ----------VFLGKHNLRQRES----SQEQSSVVRAVIHPDYDAASHDQDIMLLRLA 113

  Fly   144 LPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTEQSSLSNILLTANVSTIRHQTCRMIYRS 208
            .|..    :...:.|:.|....:.....|.:.|||:|......:.:..|.:..:..:.|...|..
Human   114 RPAK----LSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPG 174

  Fly   209 GLLPGMMCAGRLQGGTDSCQGDSGGPLVHEGRLVGVVSWG-YGCAEPGLPGVYVDVEYYRQWIE 271
            .:...|:|||..:.|.||||||||||||....|.|:|||| ..|.....||||.:|..|..||:
Human   175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	77/241 (32%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	76/239 (32%)