Protein Alignment CG14780 and PRSS8

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 96/320 - (30%)
• Similarity: 128/320 - (40%)
• Gaps: 68/320 - (21%)

  Fly    30 QSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYNNQRKRFRRAS 94
            |:||..||.|.|.:....|||       .:...|:|||:|::.:.||:||||..:...|     .
Human    42 QARITGGSSAVAGQWPWQVSI-------TYEGVHVCGGSLVSEQWVLSAAHCFPSEHHK-----E 94

  Fly    95 EFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDSMRDDVGILFLRTGLPMSPGGGVHLTVAPI 159
            .:.|.||......:.....||.:..:....::..:..:.|:.:|.|...:..|      ..:.||
Human    95 AYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFS------RYIRPI 153

  Fly   160 QL--AGQITPPGKLCQVAGWGRTEQSSLSNILLT------ANVSTIRHQTCRMIYRSGLLP---- 212
            .|  |....|.|..|.|.|||....|.   .|||      ..|..|..:||..:|.....|
Human   154 CLPAANASFPNGLHCTVTGWGHVAPSV---SLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPH 215

  Fly   213 ----GMMCAGRLQGGTDSCQGDSGGPL--VHEG--RLVGVVSWGYGCAEPGLPGVYVDVEYYRQW 269
                .|:|||.::||.|:|||||||||  ..||  .|.|:||||..|.....||||.....|..|
Human   216 FVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 280

  Fly   270 IEGR-------------SGAPHSRL-----------ATGL---FLLLLLPLLMRCSGSWL 302
            |:.:             ...|.|.|           |.||   .|.|.|.|.:.....||
Human   281 IQSKVTELQPRVVPQTQESQPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWL 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	81/257 (32%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	82/259 (32%)