Protein Alignment CG14780 and F11

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 87/284 - (30%)
• Similarity: 125/284 - (44%)
• Gaps: 44/284 - (15%)

  Fly     6 LHGCSYILFWFLLACAAADLQENQ-----QSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHIC 65
            |||...|..:.|..|.    .:|:     :.||:.|:.:...|....|::    |..:....|:|
Human   361 LHGRGGISGYTLRLCK----MDNECTTKIKPRIVGGTASVRGEWPWQVTL----HTTSPTQRHLC 417

  Fly    66 GGALIAPRKVLTAAHCLYNNQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDS 130
            ||::|..:.:||||||.|..:..:..|     |..|.||:.|.:..|....|..:.....:....
Human   418 GGSIIGNQWILTAAHCFYGVESPKILR-----VYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAE 477

  Fly   131 MRDDVGILFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGK--------LCQVAGWG-RTEQSSLS 186
            ...|:.:|.|.|            ||........|..|.|        .|.|.||| |..:..:.
Human   478 SGYDIALLKLET------------TVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQ 530

  Fly   187 NILLTANVSTIRHQTCRMIYRS-GLLPGMMCAGRLQGGTDSCQGDSGGPL--VHE--GRLVGVVS 246
            |.|..|.:..:.::.|:..||. .:...|:|||..:||.|:|:|||||||  .|.  ..|||:.|
Human   531 NTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITS 595

  Fly   247 WGYGCAEPGLPGVYVDVEYYRQWI 270
            ||.|||:...||||.:|..|..||
Human   596 WGEGCAQRERPGVYTNVVEYVDWI 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	79/252 (31%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	5/13 (38%)
		Tryp_SPc	389..619	CDD:238113	77/250 (31%)