Protein Alignment CG14780 and CFD

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 82/279 - (29%)
• Similarity: 121/279 - (43%)
• Gaps: 36/279 - (12%)

  Fly     6 LHGCSYILFWFLLACAAADLQ-----ENQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHIC 65
            :|....:....||..||...:     ...:.||:.|..|:|....::.|::|       ...|:|
Human     1 MHSWERLAVLVLLGAAACGEEAWAWAAPPRGRILGGREAEAHARPYMASVQL-------NGAHLC 58

  Fly    66 GGALIAPRKVLTAAHCLYNNQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAYMHTFSPDS 130
            ||.|:|.:.||:|||||.:....:.:      |:||..:..:......:..|..........||:
Human    59 GGVLVAEQWVLSAAHCLEDAADGKVQ------VLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDT 117

  Fly   131 MRDDVGILFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTEQS-----SLSNILL 190
            :..|:.:|.|.....:.|.    :...|.|...:...||.||.|||||....:     ||.::||
Human   118 IDHDLLLLQLSEKATLGPA----VRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLL 178

  Fly   191 TANVSTIRHQTC-RMIYRSG-LLPGMMCAGRLQGGTDSCQGDSGGPLVHEGRLVGVVSWGYG-CA 252
                ..:...|| |..:..| :...:|||.  ....|||:||||||||..|.|.|||:.|.. |.
Human   179 ----PVLDRATCNRRTHHDGAITERLMCAE--SNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCG 237

  Fly   253 EPGLPGVYVDVEYYRQWIE 271
            ....||:|..|..|..||:
Human   238 NRKKPGIYTRVASYAAWID 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	75/245 (31%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	76/247 (31%)