Protein Alignment CG14780 and KLK11

DIOPT Version :10

• Sequence 1: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 92/287 - (32%)
• Similarity: 131/287 - (45%)
• Gaps: 47/287 - (16%)

  Fly    12 ILFWFLLACAAADLQENQQSRIINGSVAKADETRHLVSI----RLLRHDNNFGSGHICGGALIAP 72
            ||...|||.|...:  ..::|||.|...|........::    |||           ||..||||
Human    35 ILQLILLALATGLV--GGETRIIKGFECKPHSQPWQAALFEKTRLL-----------CGATLIAP 86

  Fly    73 RKVLTAAHCL---------------YNNQRKRFRRASEFVVVLGTLNRFEHRNGTIVSQVSSMAY 122
            |.:|||||||               .::........|.::|.||..| .:...|...::.::.::
Human    87 RWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHN-LQKEEGCEQTRTATESF 150

  Fly   123 MHTFSPDSM-----RDDVGILFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTE- 181
            .|....:|:     |:|  |:.::...|:|    :...|.|:.|:.:....|..|.::|||.|.
Human   151 PHPGFNNSLPNKDHRND--IMLVKMASPVS----ITWAVRPLTLSSRCVTAGTSCLISGWGSTSS 209

  Fly   182 -QSSLSNILLTANVSTIRHQTCRMIYRSGLLPGMMCAGRLQGGTDSCQGDSGGPLVHEGRLVGVV 245
             |..|.:.|..||::.|.||.|...|...:...|:||...:||.||||||||||||....|.|::
Human   210 PQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGII 274

  Fly   246 SWGYG-CAEPGLPGVYVDVEYYRQWIE 271
            |||.. ||....||||..|..|..||:
Human   275 SWGQDPCAITRKPGVYTKVCKYVDWIQ 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	84/264 (32%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	84/264 (32%)