Protein Alignment O-fut2 and pofut2

DIOPT Version :10

• Sequence 1: NP_569916.1
• Gene: O-fut2 / 31098
• FlyBaseID: FBgn0027791
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001072179.1
• Gene: pofut2 / 779585
• XenbaseID: XB-GENE-1018927
• Length: 435
• Species: Xenopus tropicalis
• Alignment Length: 504
• Identity: 177/504 - (35%)
• Similarity: 247/504 - (49%)
• Gaps: 104/504 - (20%)

  Fly     4 SWPRLGFPALLLLLHLLTGSDAAVRNGTAKREIGDSRGSSGTCVKGFLQEILPLPATCPPE---- 64
            ||.    |.|||||                          |.|:.       .||..|..|
 Frog     5 SWR----PRLLLLL--------------------------GVCLS-------LLPRACGDEGQFS 32

  Fly    65 ------VLGMRGAV----YILYDVNISEGFNLRRDVYIRMAVFVRRLQRRRRFRHVRLVLPPWPR 119
                  .|.:..|.    |:|||||..||||||||||||:|..::.|.:...:   .||||||.|
 Frog    33 PGHSASSLQVGTAAFERRYLLYDVNPPEGFNLRRDVYIRVASLLKTLLKSSNW---VLVLPPWGR 94

  Fly   120 LYHWHSQGLQQSGLPWSHFFDLASLRRYAPVLDYEEFLAEQRLFGNPGAPLVHVGHAFRLQHYEV 184
            ||||.|..:.|..:||:.||||.||.:..||::||:||||.      |.|.:.  ..:.||.|..
 Frog    95 LYHWQSPDIHQVRIPWAEFFDLDSLYQNIPVIEYEDFLAES------GGPFIE--QVYVLQGYAE 151

  Fly   185 MLEQGIFRDKFERVTDKPCSEGSLSGGPLLQQAELRVGRFH---------------CVRFQGSAG 234
            ..::|.:.   |:|..:||.:       .|..:|.:.|.:.               |:..||||.
 Frog   152 GWKEGTWE---EKVDQRPCID-------QLMYSEDKNGYYRGWFWGYEETRGINVTCLSVQGSAS 206

  Fly   235 LLEKLLREAIDEDTAGPEDVDDMRTYALLSAETVLHDHWGDEHFWQARRSMRFARRLEQVAADFR 299
            ::..:|   :...||        |:..|..||.:||||:|.:.:|..||||.||:.|..|..:||
 Frog   207 IMAPVL---LKNTTA--------RSVMLDRAENLLHDHYGGKDYWDTRRSMVFAKHLRVVGDEFR 260

  Fly   300 RQALDTTDASAGVQRPAMWELERPK-RNAKGGDYLCAHLRRGDFVRSRDATTPTLKAAAQQVKQL 363
            ...|.:||.:........|...:.| .:|.||.||..||||.||:.......|:|:.||.::..|
 Frog   261 ANFLHSTDEADRTIFHEDWTKVKAKPDSALGGPYLAVHLRRKDFIWGHREDVPSLRRAADEIHSL 325

  Fly   364 LRGFNMTTVFLATDATPYELMELKELFYRFRLVHFAPESNVQRREL-KDGGVAVVDQLVCAYARY 427
            ::...:..||:||||...:|..|::|..  .:|.|  |:..:..|| ||||||::||.:||:|||
 Frog   326 MKKLKLKKVFVATDADREDLEALRKLIP--EMVRF--EATWEELELYKDGGVAIIDQWICAHARY 386

  Fly   428 FVGTYESTFTYRIYEEREILGFTQASTFNTFCKALGGSCSRNAVWPIVW 476
            |:||..|||::||:||||||.|...:|:|.||.....:|.:...|.||:
 Frog   387 FIGTSVSTFSFRIHEEREILSFNPKTTYNRFCGDKEKNCEQPTHWKIVY 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
O-fut2	NP_569916.1	O-FucT-2	73..460	CDD:211384	156/403 (39%)
pofut2	NP_001072179.1	O-FucT-2	51..420	CDD:211384	157/404 (39%)