Protein Alignment CG14785 and KLHL31

DIOPT Version :8

• Sequence 1: NP_569912.2
• Gene: CG14785 / 31094
• FlyBaseID: FBgn0027795
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_001003760.2
• Gene: KLHL31 / 401265
• HGNCID: 21353
• Length: 634
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 38/184 (21%)
• Similarity: 62/184 (34%)
• Gaps: 44/184 (24%)

  Fly   275 FLCIVGSPFFLYFTEHELTHILRNCYLSVNSEIEIFLSVVLWLEHNWLERGDCAERILAEVHFAL 339
            ||....|..|:..|..::..:|.:..|.:.|||..|...:.|||.: .:|...|..:|:.:.|..
Human   199 FLEFAESDQFMKLTFEQINELLIDDDLQLPSEIVAFQIAMKWLEFD-QKRVKYAADLLSNIRFGT 262

  Fly   340 MPTWYLCTLDRSNRCNHFARVIHSPGVQRL-----------------------IAAGLEDAITLK 381
                 :...|..|......|::......||                       |..|....:|:.
Human   263 -----ISAQDLVNYVQSVPRMMQDADCHRLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLVTVG 322

  Fly   382 SKPRFSGAALHRQRKHQEERLLVRD----WIVDTECSHHHKSHC----EQFVY 426
            .:|..:..:|.|.       :|.||    |...||......:.|    :.|:|
Human   323 GRPGLTEKSLSRD-------ILYRDPENGWSKLTEMPAKSFNQCVAVMDGFLY 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14785	NP_569912.2	BACK	256..345	CDD:197943	18/70 (26%)
		DUF4734	360..450	CDD:292506	17/99 (17%)
KLHL31	NP_001003760.2	BTB	63..164	CDD:279045
		PHA03098	73..601	CDD:222983	38/184 (21%)
		BACK	172..273	CDD:285009	20/80 (25%)
		Kelch 1	317..365		11/55 (20%)
		KELCH repeat	356..405	CDD:276965	3/14 (21%)
		Kelch 2	366..419		2/4 (50%)
		Kelch	367..419	CDD:128874	1/3 (33%)
		KELCH repeat	409..453	CDD:276965
		Kelch	420..466	CDD:128874
		Kelch 3	420..466
		Kelch_1	455..500	CDD:279660
		KELCH repeat	456..501	CDD:276965
		Kelch 4	468..513
		Kelch_1	502..552	CDD:279660
		KELCH repeat	503..551	CDD:276965
		Kelch 5	515..565
		KELCH repeat	555..602	CDD:276965
		Kelch 6	567..614

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.667	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910