DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ssx and CELF5

DIOPT Version :9

Sequence 1:	NP_569908.1	Gene:	ssx / 31086	FlyBaseID:	FBgn0024987	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_068757.2	Gene:	CELF5 / 60680	HGNCID:	14058	Length:	485	Species:	Homo sapiens

Alignment Length:	219	Identity:	59/219 - (26%)
Similarity:	103/219 - (47%)	Gaps:	29/219 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 NEGNDNSAGQQQQMQQVDRTSATNLIINYLPQDMTDRELYNLFSGCGPINTCKIMRDFKTGYSFG 135
            :.|.:...||...|:.:|   |..|.:..:|:.:.:::|..||...|.|....:::|..||...|
Human    26 SSGPEPPGGQPDGMKDLD---AIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87

  Fly   136 YGFVDYKTESDSEDAIQKLNGFYVRNKRLKVSYARP-----------GGQSIKDTNLYVINLSRN 189
            ..|:.|.....:..|...|:     .::.....|||           ||   :|..|:|..|::.
Human    88 CAFLTYCARDSAIKAQTALH-----EQKTLPGMARPIQVKPADSESRGG---RDRKLFVGMLNKQ 144

  Fly   190 INDDMLDRIFSPYGLIVQRNILRDKLTGRPRGVAFVRYNKREEAQEAIKAL--NNTVPEGGSQPI 252
            .:::.:.|:|.|:|:|.:..:||.. .|..:|.|||:::...|||.||.||  :.|:| |.|..:
Human   145 QSEEDVLRLFQPFGVIDECTVLRGP-DGSSKGCAFVKFSSHTEAQAAIHALHGSQTMP-GASSSL 207

  Fly   253 WVRLAE---EHGKAKAAQFMAQIG 273
            .|:.|:   |....:..|.:.|:|
Human   208 VVKFADTDKERTLRRMQQMVGQLG 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssx	NP_569908.1	RRM_SF	93..173	CDD:302621	18/90 (20%)
ssx	NP_569908.1	RRM_SF	179..257	CDD:302621	27/79 (34%)
CELF5	NP_068757.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..40		3/13 (23%)
		RRM1_CELF3_4_5_6	40..126	CDD:410041	20/93 (22%)
		half-pint	46..>372	CDD:130706	53/196 (27%)
		RRM2_CELF3_4_5_6	133..213	CDD:410043	28/81 (35%)
		RRM3_CELF3_4_5_6	396..474	CDD:241083
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910