Protein Alignment CG11417 and Esf1

DIOPT Version :10

• Sequence 1: NP_569906.1
• Gene: CG11417 / 31083
• FlyBaseID: FBgn0024364
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_001074559.1
• Gene: Esf1 / 66580
• MGIID: 1913830
• Length: 845
• Species: Mus musculus
• Alignment Length: 902
• Identity: 310/902 - (34%)
• Similarity: 449/902 - (49%)
• Gaps: 232/902 - (25%)

  Fly    37 SENGIWQDSRFQHLLTDPRFRGVPKVQRKVKIDKRFQGMFTDDKFKVKYTVDKYGRPVNKSNAED 101
            |:..|..|.||:.:..||||..:|:.:|||||||||:.||.|.|||:.|.|||.|||::.|..||
Mouse     3 SKQEIMDDQRFRRVSKDPRFWEMPEKERKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTED 67

  Fly   102 LRKFYELDENESSSGEEPAK-------KESDLDSEAEAEQQERRAEERAIANLEKEESNDTLESD 159
            |::||:|.:::|...:|.:|       |:....::.||:..|:..||:      |:|:..|.:.|
Mouse    68 LKRFYDLSDSDSDLSDEESKILSQKKAKQKKKQTKKEAKSIEKPIEEK------KKETKKTDQKD 126

  Fly   160 S--------SEVSQSLRQRLTNPEID-----------------YARG----------EGRLYT-D 188
            |        ||..|.::......:||                 ..||          :|:|.| |
Mouse   127 SINKHDLNNSERVQKMKNSQKPQKIDSEISPKKDNEEFLQNKKKKRGTTDLSVEALPKGKLRTKD 191

  Fly   189 SS----------------------------------------------------SDEDSDDE--- 198
            ||                                                    |||:|:||
Mouse   192 SSTSEMVKSSTMSSSKAKREKQSVVPVIMAKDNDGKMPDEDALEEDSDSASELGSDEESEDEIIS 256

  Fly   199 ----------------------------------DEGPELQ------------------------ 205
                                              |.||:|.
Mouse   257 DGKTSADEDESEEEDEEEEEDSEEEEEEEEEDESDSGPDLARGKGNVETSSEDEDDLADLFPEEP 321

  Fly   206 -IDHVWGELDNDAEHTEESTRRLAVCNMDWDRIRAEDLMVMLSSFLPPGGSILSVKIYPSEFGKA 269
             .:|.|.|||.||...:|.|||||||||||||::|:||:.:.:||.|.||.:.|||||||||||.
Mouse   322 GFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVFSVKIYPSEFGKE 386

  Fly   270 RMAEEEVHGPKELVERVEPEDDSDEELVRQQDSDAEEGEDYHMEKLRQYQLNRLRYYYAVVECDS 334
            ||.||:|.||.||:...|               ||.|.:....||||.||..||:|||||.||||
Mouse   387 RMKEEQVQGPVELLSIPE---------------DAPEKDWASREKLRDYQFKRLKYYYAVAECDS 436

  Fly   335 IDTADKVYKECDGIEYESSATRVDLRFIPDDTSFEEDTPSDECFELPDASSYKPRQFTTTALQQA 399
            .:||.|:|::|||:|:|||.:.:||||||||.:| :|.|.|...|: |.::|||:.||:.|:..:
Mouse   437 PETASKIYEDCDGLEFESSCSFIDLRFIPDDITF-DDEPKDVALEV-DLTAYKPKYFTSAAMGTS 499

  Fly   400 KVDLTWDETALDR-RELGDKLSSGQVDKLTDKELRQIVAYSSEEEDSEAEESP-AEEAAQKAVSE 462
            .|::|||||..:| ..|..|...   |:|.|.:.:..:|.|||:|: |.||:| .||...  :.|
Mouse   500 TVEITWDETDHERITTLNRKFKK---DELLDMDFQAYLASSSEDEE-EVEEAPEGEEGVN--IGE 558

  Fly   463 DPQKSKPKKTSK--QERIATYKNLLADILEQEKKEKEQKYEMEMTW---NVEPQHEEAQPEQQAQ 522
            |   .|.||:.|  :|:||.|:.||..|.|:|||.||...|||:.|   ..|...|..:.:.:.:
Mouse   559 D---GKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGK 620

  Fly   523 AELTPIEKVIQKRSEKNRQRKEQRRQRQIEARGGDAGEDSDESMVPDGIDLNDAYFAEEFANGDY 587
            .:|||.|:.::|:.||.|.:|:|:..         |.|||::.: |..:|.||.|||||.
Mouse   621 DKLTPWEQFLEKKKEKKRLKKKQKAL---------AEEDSEDEL-PSDVDFNDPYFAEEV----- 670

  Fly   588 APPKTKQDKKKKKKKGKD--DGEEDVEAKRQEKELELLLDDGDGRDEKQHFSLTKILKKEEQEAS 650
               |....|||..|..||  ..||:.:.::|:.|:.||:.| :..|.|:||:..||::.:..
Mouse   671 ---KKIGIKKKSMKSAKDSASSEEETDLEKQKAEMALLVMD-EEEDSKKHFNYDKIVEHQNL--- 728

  Fly   651 GSKRKRRQKLKKSKNQPQNAEKLDDDFQVNLNDNRFSAVYKSHEYNIDPTHSHYKPTKGMQQIIG 715
             ||:|::|.:||.       |.::|||:||::|.||.|:|.||.:|:||:..::|.||.|::|:.
Mouse   729 -SKKKKKQLMKKK-------ELVEDDFEVNVSDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILE 785

  Fly   716 EKLKRRKEQGEGGAANGDADGDEQVAPKRSKQQLEQ--NALVKSLKRKIQLQQQGQK 770
            || .|.:|:.|...........:.......||.::.  :.|:||:|.|.: |.|.:|
Mouse   786 EK-ARHRERKEELLIQAVERAQQDTGKPTQKQPMDPALSMLIKSVKNKTE-QFQARK 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11417	NP_569906.1	COG5638	44..763	CDD:227925	305/886 (34%)
Esf1	NP_001074559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..321		49/272 (18%)
		COG5638	295..798	CDD:227925	225/559 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	536..570		16/39 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	634..660		10/35 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	676..696		8/19 (42%)