DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11403 and UVH6

DIOPT Version :9

Sequence 1:	NP_569898.1	Gene:	CG11403 / 31072	FlyBaseID:	FBgn0026876	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_171818.1	Gene:	UVH6 / 839557	AraportID:	AT1G03190	Length:	758	Species:	Arabidopsis thaliana

Alignment Length:	755	Identity:	199/755 - (26%)
Similarity:	322/755 - (42%)	Gaps:	128/755 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 VHPGKLE---ELEKDLDPESDSDSEHETADGPQEAAED---RYR------PVQIFFCSRTHSQLA 201
            ::|.:.|   ||::.||.:.....|..|..|...|...   .||      |:::.:|:||..::.
plant    17 IYPEQYEYMVELKRALDAKGHCLLEMPTGTGKTIALLSLITSYRLSRPDSPIKLVYCTRTVHEME 81

  Fly   202 QIVAELRKTPHGQSVR---------SISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKARPN 257
            :.:.|| |..|...||         ::.|.||:.||.|..|     :...|...:|.|.:| |..
plant    82 KTLGEL-KLLHDYQVRHLGTQAKILALGLSSRKNLCVNTKV-----LAAENRDSVDAACRK-RTA 139

  Fly   258 PSKKSRLTAEAN-SRCPF-----KAASLVESLRDLALTEP--LDIEELANEGTACGGCSYYASRS 314
            ...::..|...| ..|.|     |||       :.||..|  ..:|:|...|...|.|.|:.:|.
plant   140 SWVRALSTENPNVELCDFFENYEKAA-------ENALLPPGVYTLEDLRAFGKNRGWCPYFLARH 197

  Fly   315 AVEHAQLILLPYQLLLQKSARNQLGISL-KGSIVIVDEAHNLLDSVAQLHGSEISRQQLERAKVQ 378
            .::.|.:|:..||.||.......:...| |.|:|:.|||||:.:...:.....:.|..||.|
plant   198 MIQFANVIVYSYQYLLDPKVAGFISKELQKESVVVFDEAHNIDNVCIEALSVSVRRVTLEGA--- 259

  Fly   379 ISGYKDHFQKRFTTKNLLKINQIIFIIR------------RLLKILDQRKELQSNGCSMMRT--- 428
                         .:||.||.|.|...:            ||::.|..|.:| |.|...:..
plant   260 -------------NRNLNKIRQEIDRFKATDAGRLRAEYNRLVEGLALRGDL-SGGDQWLANPAL 310

  Fly   429 -YELTAEGDFFNIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQAPVSTARSLILQRLASE 492
             :::..|....||...|......|    |.:|....|::.|  ..|.::|||...||..|....:
plant   311 PHDILKEAVPGNIRRAEHFVHVLR----RLLQYLGVRLDTE--NVEKESPVSFVSSLNSQAGIEQ 369

  Fly   493 QKLK---EKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPLLAFLETLTSNAEDG 554
            :.||   ::.:|:...:|..:.::..                    ||:.:..|...:.:.|...
plant   370 KTLKFCYDRLQSLMLTLEITDTDEFL--------------------PIQTVCDFATLVGTYARGF 414

  Fly   555 RILVDPVGGTLKYILLDPAEQFA---------DIVAEARAIVIAGGTMQPTKELKEQL--FTGCH 608
            .|:::|....:.:| .||..|.:         .:....:::||..||:.|. :|..:|  ||
plant   415 SIIIEPYDERMPHI-PDPILQLSCHDASLAIKPVFDRFQSVVITSGTLSPI-DLYPRLLNFT--- 474

  Fly   609 DRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVPGGVVCF 673
             .:|.|.:...:..|.|.|.|::.|....|:|.||..|....::|....:|..:..:||.|||||
plant   475 -PVVSRSFKMSMTRDCICPMVLTRGSDQLPVSTKFDMRSDPGVVRNYGKLLVEMVSIVPDGVVCF 538

  Fly   674 LPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGSAEQ--LLDNYALAIKRPASYGALLLSVVG 736
            ..||.|:|.:.....::|.|:.|..:|.||.|.....|.  .||||..|.  ....||:..||..
plant   539 FVSYSYMDGIIATWNETGILKEIMQQKLVFIETQDVVETTLALDNYRRAC--DCGRGAVFFSVAR 601

  Fly   737 GKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGPGAGNEYYENLCVKAVNQCIG 801
            ||::||::|....||.|::.|:|:..:||..||.|:::|.:......| ::.....::...||:|
plant   602 GKVAEGIDFDRHYGRLVVMYGVPFQYTLSKILRARLEYLHDTFQIKEG-DFLTFDALRQAAQCVG 665

  Fly   802 RAVRHIKDYACVYLLDKRFADPKIRGKLPKWISRHIVEAN 841
            |.:|...||..:...|||::....|.|||.||..|:.:|:
plant   666 RVIRSKADYGMMIFADKRYSRHDKRSKLPGWILSHLRDAH 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DinG	15..841	CDD:224120	198/753 (26%)
		DEXDc2	16..394	CDD:214693	70/274 (26%)
		Helicase_C_2	659..836	CDD:290046	62/178 (35%)
UVH6	NP_171818.1	rad3	7..714	CDD:273169	199/755 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186062at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820