Protein Alignment CG11403 and rtel1

DIOPT Version :10

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001013328.3
• Gene: rtel1 / 503732
• ZFINID: ZDB-GENE-050306-11
• Length: 1177
• Species: Danio rerio
• Alignment Length: 893
• Identity: 229/893 - (25%)
• Similarity: 349/893 - (39%)
• Gaps: 209/893 - (23%)

  Fly    20 FPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEMLARIRG 84
            ||::||..||..|.::.:.|::...|:.||||||||:|.|.|..|.|....::.:....:....|
Zfish    13 FPFTPYPCQEDYMSKVIECLQKKVNGVLESPTGTGKTLCLLCSTLAWRDHFKDTISARKITERMG 77

  Fly    85 VEQELAKLKEESEQSSNWLESQGKSRAQRAELLRLQHLQALLDKQEQQLDQIRKGAKKHKRQGRV 149
            ..:..|     ....|:|    |.:
Zfish    78 GAELFA-----DRPMSSW----GTA---------------------------------------- 93

  Fly   150 HPGKLEELEKDLDPESDSDSEHETADGPQEAAEDRYRPVQIFFCSRTHSQLAQIVAELRKTPHGQ 214
                          .:|.|:.....|.|           :|.:.|||||||.|:|.||:.|.:..
Zfish    94 --------------ATDGDTPTYYTDIP-----------KIIYASRTHSQLTQVVNELKNTSYRP 133

  Fly   215 SVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKARPNPSKKSRLTAEANSRCPFKAASL 279
            .:  ..||||:|||.|..|  ::|                ..|..|.....|:.:||......::
Zfish   134 KI--CVLGSREQLCINQEV--MRH----------------ESNHIKVHMCRAKVSSRSCIFYNNV 178

  Fly   280 VESLRDLALTEP-LDIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLK 343
            .|...|..:... ||:|:|...|.....|.||.|||..:||.:|.:||..||...:|....|.||
Zfish   179 DEKSTDKEIVNSILDVEDLVKTGKKQRVCPYYLSRSLKQHADVIFMPYNYLLDPKSRRAHNIELK 243

  Fly   344 GSIVIVDEAHNL-----------------------LDSVAQLHGSEISRQQLERAKVQISGYKDH 385
            |::||.|||||:                       :|.:.:...|:||:.. ......:......
Zfish   244 GAVVIFDEAHNVEKMCEESTSFDLTPHDLISAIEAVDRLLREQASDISKAD-SAEDFNVESLNSG 307

  Fly   386 FQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDFFNIDLCELLDFCA 450
            .:...||  :.|:.||:..:...:...:.....|.          :|..|.|. .:|.|:.:..:
Zfish   308 LKMDITT--IAKVKQILMDLETAINDFEMPANNQG----------ITKPGSFI-FELFEMANVNS 359

  Fly   451 RTRFARKVQGRADRMER-----EPRP-----SENQAPVSTARSLILQRLASEQKLKEKT----KS 501
            :|:     ....:.||:     ..||     :.....|:....|:.....:|...|.:|    |.
Zfish   360 KTK-----TETVEAMEQITGYLAGRPGVFLNTSGLQKVADIIQLVFVAEPAEGSKKSQTGNSLKE 419

  Fly   502 VKRRVEDINKEDKAEELQEQQKPTKKPVEEV-APSPIRPLLAFLETLTSNAEDGRILVDPVGGTL 565
            .|..:...|...|           ||.:.:| |.|.|:                     ..|..|
Zfish   420 FKVHIHPDNSNFK-----------KKQITDVWASSSIK---------------------KQGNVL 452

  Fly   566 KYILLDPAEQFADIV-AEARAIVIAGGTMQPTKELKEQLFTGCHDRL---VERFYNHVVANDAIL 626
            .|....|.....::: .|.|.|::..||:.|...     || |..::   |.....||:..|.|.
Zfish   453 SYWCFSPGFSMQELLRQEVRCIILTSGTLSPLSS-----FT-CEMQIPFPVSLENPHVIQRDQIF 511

  Fly   627 PFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVPGGVVCFLPSYEYLDKVYKYLEQSG 691
            ..:|..||.|..||..|..|...|.:..:...|.||.:|||.|::.|.|||..:||..::....|
Zfish   512 VSIIEKGPDGVQLSTAFDRRFVPENMSSMGNTLVNLSRVVPHGLLVFFPSYPVMDKTLEFWRAKG 576

  Fly   692 TLETISGRKSVFREV--SGSAEQLLDNYALAIKRPASYGALLLSVVGGKLSEGLNFADDLGRAVL 754
            ..:.|...|.:|.|.  .|:..:::|.|...:..|.|.|....:|..||.||||:|||..||.|:
Zfish   577 HADRIENVKPMFVEPRGKGTFTEVIDGYYGKVDDPNSSGGSFFAVCRGKASEGLDFADTYGRGVV 641

  Fly   755 VVGLPYSNSLSPELRQRMQHLDE----KLGPG----AGNEYYENLCVKAVNQCIGRAVRHIKDYA 811
            :.|||:...:.|.:..:||:|||    |:. |    .|.|:|.....:||||.|||.:||.:||.
Zfish   642 ITGLPFPPRMDPRVVLKMQYLDEMCRNKIS-GVKYLTGQEWYRQQASRAVNQAIGRVIRHREDYG 705

  Fly   812 CVYLLDKRFADPKIRGKLPKWISRHIVEANAANGGFGAVQGRTARFFK 859
            .::|.|.||.....|.:||.|:..::    ....|||.:....|:||:
Zfish   706 AIFLCDHRFKSADARNQLPSWVRPYV----KIYDGFGTMVRDVAQFFR 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120	16/58 (28%)
		rad3	187..837	CDD:273169	192/702 (27%)
rtel1	NP_001013328.3	Nuclear localization signal. /evidence=ECO:0000255|HAMAP-Rule:MF_03065	151..167		4/31 (13%)
		DEAH box	250..253		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	847..869
		Nuclear localization signal. /evidence=ECO:0000255|HAMAP-Rule:MF_03065	883..889