DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11403 and Ddx11

DIOPT Version :10

Sequence 1:NP_569898.1 Gene:CG11403 / 31072 FlyBaseID:FBgn0026876 Length:861 Species:Drosophila melanogaster
Sequence 2:XP_063123411.1 Gene:Ddx11 / 316767 RGDID:1306675 Length:922 Species:Rattus norvegicus


Alignment Length:915 Identity:342/915 - (37%)
Similarity:502/915 - (54%) Gaps:106/915 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 GAQEFGFPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEE---LVR 75
            |...|.||:.||.||:..|.||::|||.|::|||||||||||||:|.||||:||...|:   ...
  Rat    25 GGIHFPFPFPPYPIQKDFMAELYKVLEAGKIGIFESPTGTGKSLSLICGALSWLRDFEQKKLQAE 89

  Fly    76 TEMLARIRGVEQ-------ELAKLKEESEQ-----SSNWLESQGKSRAQRAELLRLQHLQALLDK 128
            ..:||...|...       ..:..:|.|:.     ..:|:....:.:.:|..:.||:..|....|
  Rat    90 AGLLAPASGPTSSGRNSVLSSSSCQEPSDTLRPAGDPDWVTEFVQKKEERDLVERLREEQLRRRK 154

  Fly   129 QEQQLDQI-----RKGAKKHKRQGRVHPGKLEELEKDL-----------------------DPES 165
            :|::|.::     |:.|.|..||.......|..|.:::                       :.||
  Rat   155 REERLQEVCQDGRRRFAAKRSRQEEEETETLLRLSREMLAADTAPEQLGQLECGEEHLVLAEYES 219

  Fly   166 DSDSEHETADGPQEAAEDRYRPVQIFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGN 230
            |.:.....||..::..|:.: ..:|::||||||||||.|.|::|:|.|:..|.:||||||.||.|
  Rat   220 DEERRGSRADEGEDDLEEEH-ITKIYYCSRTHSQLAQFVREVQKSPFGKETRLVSLGSRQSLCVN 283

  Fly   231 PAVRKLKHVGLMNERCLDMAT---KKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLALTEPL 292
            ..|:.|..|.|||:||:||..   ||.|....|..|...:..:.|||.....:|.|||..|.|..
  Rat   284 EDVKSLGSVHLMNDRCVDMQRRKHKKMRIGEDKPKRRRQKMQASCPFYNHEQMELLRDEILLEVK 348

  Fly   293 DIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHNLLD 357
            |:|:|...|.....|.||.||.|:..|||::|||.:||..:.|...||.|:|.:||:||||||:|
  Rat   349 DMEQLVALGKEAQACPYYGSRFAIPAAQLVVLPYPMLLHAATRQAAGIRLQGQVVIIDEAHNLID 413

  Fly   358 SVAQLHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNG 422
            ::..:|.:|::..||.:|..|:..|.:.::||...|||:.|.||::::.:.:.:|....:...:.
  Rat   414 TITNIHSTEVNGSQLCQAHSQLLQYMERYRKRLKAKNLMYIKQILYLLDKFVAVLGGNVKQNPST 478

  Fly   423 CSMMRT-YELTAEGDFF------NIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQAPVST 480
            .|:.:| .||.:..||.      ||:|.::..:..::..:||:.|                 .:.
  Rat   479 QSLPQTGSELQSINDFLFQSQVDNINLFKVQRYLEKSMLSRKLFG-----------------FTE 526

  Fly   481 ARSLILQRLASEQKLKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPLLAFLE 545
            ...::|..| |:.:........::.::.:......:.|:|.|....:|.     ||:..:.||||
  Rat   527 CFGVVLPSL-SDSEENRGLGGFQQFLKSLQSGPPEDSLEEGQAVALRPA-----SPLMHIEAFLE 585

  Fly   546 TLTSNAEDGRILVDPVG----GTLKYILLDPAEQFADIVAEARAIVIAGGTMQPTKELKEQLFTG 606
            .||:..:|||::|:..|    .:||::||:||..||.:|.|.||:|||||||||..:.:|||. .
  Rat   586 ALTTANQDGRVIVNRQGSVGQSSLKFLLLNPAVHFAQVVKECRALVIAGGTMQPVSDFREQLL-A 649

  Fly   607 CH----DRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVP 667
            |.    .|:||....||:..|.|||.:|.:|||...|.|.:..|...:|:.|...||.|||.|||
  Rat   650 CSGVEASRVVEFSCGHVIPPDNILPLIICSGPSNQQLEFTYQRRELPQMMEETGRILCNLCNVVP 714

  Fly   668 GGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREV--SGSAEQLLDNYALAIKRPAS---- 726
            ||:||||||||||.:|:.:.:::|.|..:|.||.:|:|.  :...||:|..|:..|   ||    
  Rat   715 GGMVCFLPSYEYLRQVHAHWDKTGLLARLSVRKKIFQEPKRASQVEQVLTAYSTCI---ASCSHS 776

  Fly   727 ----YGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKL-----GPG 782
                .|||||||||||:|||:||:|||||.|::||:||.|..||||:::|.:||:.:     .|.
  Rat   777 EGHLTGALLLSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMAYLDQTIPRTHGQPP 841

  Fly   783 AGNEYYENLCVKAVNQCIGRAVRHIKDYACVYLLDKRFADPKIRGKLPKWISRHIVEANAANG-G 846
            .|....||||:||:||.||||:||.||:|.:.|||.|:|.|.|..|||.|| |..||..|..| .
  Rat   842 PGTVLIENLCMKAINQSIGRAIRHQKDFASIVLLDHRYARPSILAKLPAWI-RDRVEVKATFGPA 905

  Fly   847 FGAVQ 851
            |.|::
  Rat   906 FAAMR 910

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11403NP_569898.1 DEAD-like_helicase_N 42..>101 CDD:475120 27/73 (37%)
rad3 187..837 CDD:273169 274/682 (40%)
Ddx11XP_063123411.1 None

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