Protein Alignment CG11403 and brip1

DIOPT Version :10

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_002933884.1
• Gene: brip1 / 100489959
• XenbaseID: XB-GENE-492370
• Length: 1229
• Species: Xenopus tropicalis
• Alignment Length: 980
• Identity: 248/980 - (25%)
• Similarity: 393/980 - (40%)
• Gaps: 239/980 - (24%)

  Fly     1 MSQYTPNQRLDTPGAQEFGFPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALT 65
            :|:|       |.|..:..||...|..|..:|..:.:.|...|..:.|||||:||||.|.|.||.
 Frog     5 LSEY-------TIGGVKILFPCRAYPSQLAMMNSIMRGLNCKQHCLLESPTGSGKSLALLCSALA 62

  Fly    66 WLARHEELVRTEMLARIRGVEQELAK------------LKEESEQS---------------SNWL 103
            |    ::.:..:.....:..|:|..|            |:...|.|               ||:.
 Frog    63 W----QQSLYGKQAVDEKSNEKECTKMERVTPCCCSCHLRNSDELSFNSSNRQMNSTDSTPSNFQ 123

  Fly   104 ESQGKSRAQRAELLRLQHLQALLDKQEQQLDQIRKGAKKHKRQGRVHPGKLEEL----------- 157
            .:........|:|...:....:.|:.:......::..:.|..|.:....:..|.
 Frog   124 GASSNKTTLAAKLCAKKQASFIADQDDDFQTDRKRIRQSHDEQQQAKKRRCYEKGVQFIDDDFNR 188

  Fly   158 -EKDLDPESD-------------SDSEHET-------ADGPQEAAEDRY------------RPVQ 189
             ..|||..:.             |.|.|..       .|| |...||:.            :..:
 Frog   189 NHTDLDSHNQKKASMDSCPEVIASSSNHSVGPCSLCLCDG-QTKEEDKAIEKGKKENGEKPKVPK 252

  Fly   190 IFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKA 254
            |||.:|||.|:|||..|||:|.: .|||...|.||:..|.:|.:...:     ||:|
 Frog   253 IFFGTRTHKQIAQITRELRRTAY-SSVRMTILSSREHTCVHPDIHSNR-----NEKC-------- 303

  Fly   255 RPNPSKKSRLTAEANSRCPFKAASLVESLRDLAL-------TEPLDIEELANEGTACGGCSYYAS 312
                  |..|.|:....|.|...  |:.:.:..|       .:..|||||...|.....|.|:|:
 Frog   304 ------KELLEAKDGHSCRFYHG--VQKMNEQNLLKYRHGVDKAWDIEELVGLGKRLRACPYFAA 360

  Fly   313 RSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHNLLDSVAQLHGSEISRQQLERAKV 377
            |..::.|.::..||..||....|..:.|.|:|.:||:|||||:.|...:......|.:||..|:.
 Frog   361 RELMQEADIVFCPYNYLLDSQIRESMDIFLEGQVVILDEAHNIEDCARESASFSCSDEQLMYARD 425

  Fly   378 QISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDFFNIDL 442
            :|....:|.                      :::.|..              .|.|        :
 Frog   426 EIDSMVNHG----------------------IRVSDHE--------------PLRA--------V 446

  Fly   443 CELLDFCARTRFARKVQGRADRMEREPRPSENQAPVSTARSL--ILQRL----ASEQKLKEKTKS 501
            |..|     |.:.|:...:.  :|||   .|....|...:.:  |...:    |:...||....:
 Frog   447 CYSL-----TNWIRECSDQL--VERE---YEASCKVWNGKEILAIFHDMGITNATFPLLKANLAA 501

  Fly   502 VKRRVEDINKEDKAEELQEQQK----PTKKPVEEVAPSPIRPLLAFLETLTSN----AEDGRI-- 556
            |      :.||:|...|..|:.    ||..|..::.   ::.|...|:.|...    |||.||
 Frog   502 V------VEKEEKITMLHGQENVIKIPTLSPQTQMV---LKGLFLVLDYLFRQNNRFAEDYRIAL 557

  Fly   557 -----------LVDPVG-----------------GTLKYILLDPAEQFADIVAEARAIVIAGGTM 593
                       :.|..|                 .||.:..|:||..|:|:.:.||.||:..||:
 Frog   558 QQSYTWANRQDIPDENGFFARPRNRRAVRQKIMVYTLNFWCLNPAVAFSDLSSNARTIVLTSGTL 622

  Fly   594 QPTKELKEQL---FTGCHDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLREL 655
            .|......:|   |:      ::...|||:....:....:..||.|..|...|.|..:.:...|:
 Frog   623 SPMGSFSSELGVKFS------IQLEANHVIHKSQVWVGTVGAGPKGRKLCATFQHTETFDFQDEI 681

  Fly   656 SMILRNLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSG----SAEQLLDN 716
            ..:|.::||.|..||:||||||:.|:|:......:|..|.:...|:|.:|..|    ..:::|..
 Frog   682 GALLLSVCQTVSHGVLCFLPSYKMLEKLKDRWMHTGLWENLERIKTVIKEPQGGDKTDFDKMLQM 746

  Fly   717 YALAIK-RPASYGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSN--SLSPELRQRM--QHLD 776
            |..||: :....||||::|..||:||||:|:|:..|||:.||:|:.|  .|..||:::.  ||..
 Frog   747 YYDAIRYKGEKDGALLIAVCRGKVSEGLDFSDNNARAVVTVGIPFPNIKDLQVELKRKYNDQHAK 811

  Fly   777 EKLGPGAGNEYYENLCVKAVNQCIGRAVRHIKDYACVYLLDKRF-ADPKIRGKLPKWISRHIVEA 840
            .: |...|:::||....:|:||.:||.:||..|:..:.|:|.|| ::||....|.||:.:.:...
 Frog   812 SR-GLLPGSQWYEIQAYRALNQALGRCIRHKNDWGALILVDDRFRSNPKYITGLSKWVRQLVQHH 875

  Fly   841 NAANG 845
            :..||
 Frog   876 STFNG 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120	21/85 (25%)
		rad3	187..837	CDD:273169	196/713 (27%)
brip1	XP_002933884.1	DEAD-like_helicase_N	43..>68	CDD:475120	14/28 (50%)
		rad3	246..885	CDD:273169	198/727 (27%)