Protein Alignment eIF4E7 and CDC33

DIOPT Version :8

• Sequence 1: NP_726718.1
• Gene: eIF4E7 / 31059
• FlyBaseID: FBgn0040368
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_014502.1
• Gene: CDC33 / 854026
• SGDID: S000005499
• Length: 213
• Species: Saccharomyces cerevisiae
• Alignment Length: 201
• Identity: 74/202 (37%)
• Similarity: 117/202 (58%)
• Gaps: 11/202 (5%)

  Fly   222 EFLSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLEN--DRNKSWEEMLHKVTSFDTVE 284
            |.:|:::......|:.:::|..    |.:||||..|||||.:.  |:::||.::|..||||.|||
Yeast    12 ENVSVDDTTATPKTVLSDSAHF----DVKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVE 72

  Fly   285 KFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLT-KSAKMALDSFWMDAML 348
            :||::|.:|..|.||.|.|||.:|:..:||.||||||..||:|...|. |.|.  :|..|:..:|
Yeast    73 EFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLRGKGAD--IDELWLRTLL 135

  Fly   349 CLIGEACKHSD-DLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRKVLRMDNIYVLEYQLH 412
            .:|||.....| .:.|||::||...||.::| ....::..:|.||...::||::.:...||:..|
Yeast   136 AVIGETIDEDDSQINGVVLSIRKGGNKFALW-TKSEDKEPLLRIGGKFKQVLKLTDDGHLEFFPH 199

  Fly   413 KDSKDK 418
            ..:..:
Yeast   200 SSANGR 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E7	NP_726718.1	IF4E	255..409	CDD:279921	64/158 (41%)
CDC33	NP_014502.1	CDC33	1..213	CDD:227386	74/202 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C5150048
eggNOG	1	0.900				E1_COG5053
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1129
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000440
OrthoInspector	1	1.000				T634585
orthoMCL	1	0.900				OOG5_127278
Panther	1	1.100			O	PTHR11960
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R595
TreeFam	1	0.960
	11	10.780