Protein Alignment eIF4E7 and Eif4e

DIOPT Version :8

• Sequence 1: NP_726718.1
• Gene: eIF4E7 / 31059
• FlyBaseID: FBgn0040368
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_446426.1
• Gene: Eif4e / 117045
• RGDID: 69647
• Length: 217
• Species: Rattus norvegicus
• Alignment Length: 240
• Identity: 99/241 (41%)
• Similarity: 137/241 (57%)
• Gaps: 32/241 (13%)

  Fly   196 LEPRIKQNTCPPAKKEDAVVAFDNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQ----HPLNNC 256
            :||.....|.||..:|:                |.:.:          .||.:|:    |||.|.
  Rat     4 VEPETTPTTNPPPAEEE----------------KTESN----------QEVANPEHYIKHPLQNR 42

  Fly   257 WTLWYLENDRNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEAN 321
            |.||:.:||::|:|:..|..::.|||||.||:|..||:..|.||.|.||||||.||.||||||.|
  Rat    43 WALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKN 107

  Fly   322 VNGGRWVINLTKSAKMA-LDSFWMDAMLCLIGEAC-KHSDDLCGVVVNIRGKSNKISIWNADGGN 384
            ..||||:|.|.|..:.: ||.||::.:||||||:. .:|||:||.|||:|.|.:||:||..:..|
  Rat   108 KRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECEN 172

  Fly   385 QTTVLEIGRILRKVLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV 429
            :..|..|||:.::.|.:....|:.||.|.|:..|.|||.|..:.|
  Rat   173 RDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E7	NP_726718.1	IF4E	255..409	CDD:279921	76/156 (49%)
Eif4e	NP_446426.1	EIF4EBP1/2/3 binding. {ECO:0000250}	37..40		3/3 (100%)
		IF4E	38..196	CDD:307672	78/158 (49%)
		7-methylguanosine-containing mRNA cap binding. {ECO:0000250}	56..57		1/1 (100%)
		EIF4EBP1/2/3 binding. {ECO:0000250}	73..77		2/4 (50%)
		7-methylguanosine-containing mRNA cap binding. {ECO:0000250}	102..103		1/1 (100%)
		EIF4EBP1/2/3 binding. {ECO:0000250}	132..139		4/7 (57%)
		7-methylguanosine-containing mRNA cap binding. {ECO:0000250}	157..162		2/5 (40%)
		7-methylguanosine-containing mRNA cap binding. {ECO:0000250}	205..207		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C106102075
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000
Homologene	1	1.000				H123817
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3477
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1394271at2759
OrthoFinder	1	1.000				FOG0000440
OrthoInspector	1	1.000				T617871
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11960
Phylome	1	0.910		0.800	Consistency score
TreeFam	0	0.000	Not matched by this tool.
	9	9.000