Protein Alignment eIF4E7 and Eif4e

DIOPT Version :10

• Sequence 1: NP_726718.1
• Gene: eIF4E7 / 31059
• FlyBaseID: FBgn0040368
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_446426.1
• Gene: Eif4e / 117045
• RGDID: 69647
• Length: 217
• Species: Rattus norvegicus
• Alignment Length: 240
• Identity: 99/240 - (41%)
• Similarity: 137/240 - (57%)
• Gaps: 32/240 - (13%)

  Fly   196 LEPRIKQNTCPPAKKEDAVVAFDNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQ----HPLNNC 256
            :||.....|.||..:|:                |.:.:          .||.:|:    |||.|.
  Rat     4 VEPETTPTTNPPPAEEE----------------KTESN----------QEVANPEHYIKHPLQNR 42

  Fly   257 WTLWYLENDRNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEAN 321
            |.||:.:||::|:|:..|..::.|||||.||:|..||:..|.||.|.||||||.||.||||||.|
  Rat    43 WALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKN 107

  Fly   322 VNGGRWVINLTKSAKMA-LDSFWMDAMLCLIGEAC-KHSDDLCGVVVNIRGKSNKISIWNADGGN 384
            ..||||:|.|.|..:.: ||.||::.:||||||:. .:|||:||.|||:|.|.:||:||..:..|
  Rat   108 KRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECEN 172

  Fly   385 QTTVLEIGRILRKVLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV 429
            :..|..|||:.::.|.:....|:.||.|.|:..|.|||.|..:.|
  Rat   173 RDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E7	NP_726718.1	IF4E	252..409	CDD:460281	78/158 (49%)
Eif4e	NP_446426.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		7/48 (15%)
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250|UniProtKB:P06730	37..40		2/2 (100%)
		IF4E	38..197	CDD:460281	78/158 (49%)
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250|UniProtKB:P06730	73..77		2/3 (67%)
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250|UniProtKB:P06730	132..139		3/6 (50%)