Protein Alignment CG3703 and Rundc1

DIOPT Version :10

• Sequence 1: NP_569874.1
• Gene: CG3703 / 31045
• FlyBaseID: FBgn0040348
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_001385698.1
• Gene: Rundc1 / 303552
• RGDID: 1307490
• Length: 615
• Species: Rattus norvegicus
• Alignment Length: 728
• Identity: 243/728 - (33%)
• Similarity: 347/728 - (47%)
• Gaps: 150/728 - (20%)

  Fly    16 STIEGQLPAGPV------RAEDEEEEVEVEQEQQELLSERWSPLGANYDDANSASSGVDCELEPG 74
            :|:|.....|.|      :|:|||||.:.|:......:.||:|:||..:....|::..:   |..
  Rat     2 ATVEVATELGTVVTAVGPKAKDEEEEEDEEESLPPCETVRWAPVGAVAEAGPGAATFSE---EAA 63

  Fly    75 LEKSEARRGSTGSELAR-LRSIEEEQELLTSSLLALTSHFAHVQLRVRQIVEAPAEERDQLLRDL 138
            .|:..|..||......| ||.::.|:..|.|:||||:||||.||.|:||:|.....|:.:|||:|
  Rat    64 AEEPGAAPGSPPDATVRTLRRLQAERRQLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLREL 128

  Fly   139 EDFAFQGIP---------DAVQSKESH---PDKP------ASDGEKDHGPDSQ------LIQQLK 179
            |||||:|.|         |...|:||.   .|:|      .|:.||....::|      ||.|||
  Rat   129 EDFAFRGCPHVLGYEGLEDPCDSEESDVLPGDRPRVRGEVQSEQEKRERLETQREKQKELILQLK 193

  Fly   180 SQLTELEQIAYEAGEPGILPQHVLLEKQKFILDELRAKLNLQVEQHELPALSTEQLRHQVDNAIG 244
            :||.:||..||:.|....|||.|:||:|:.|:|||..||::.:.: ::.:||||:||.:||.|:.
  Rat   194 TQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNE-DISSLSTEELRQRVDAAVA 257

  Fly   245 EFVGPLKMKEQLVAQLKTQITDLERFIAFLQCDAIEGSVGDRLKLLSGAYNSYAAKQTARSSQAS 309
            :.|.|.::|||||.||||||.|||.||:|:|     ..||..|:  :|.:     .:...|.:|.
  Rat   258 QIVNPARVKEQLVEQLKTQIRDLEMFISFIQ-----DEVGSPLQ--TGGH-----CECKTSGKAG 310

  Fly   310 YVATNAPATTATTPPSSGLGAHSSGESLHSKAHGLLDKASVLMQMFASTHLVKPRTHDEFQQNSL 374
            ..:|.  |.::|.||..........:.:......|:.:|..:.|:||.:.|  .....:..|...
  Rat   311 ISSTR--AGSSTLPPGPDKAKAEDTKWVRETGLHLMRRALAVFQIFAVSQL--GCATGQIPQTLW 371

  Fly   375 KKTHKGNHWGDLRAQLEVDIQEVAALAATLSCDREKLANIKRALRKQQQQAESTEFSDTGNPVIN 439
            ::......:..|..:||            ||.||.|    :.|||.|
  Rat   372 QRGQADRDYSPLLKRLE------------LSVDRVK----QLALRHQ------------------ 402

  Fly   440 SQNGALTLPPRCRRAVPTGHELAPYASGGAISSDSDEDISYSNFEWEKESKSRRTTHARGDSIAT 504
                            |..|         .|:|.:.:|:|..
  Rat   403 ----------------PHDH---------VITSANLQDLSLG----------------------- 419

  Fly   505 IGR-ELTTVVRKNFARTLQQLIQHGLRIPAESAASSLMVPFMRCLHPGPPVVPPAVGGDSQFLGL 568
             || |||..|||.....::.|:.|||.  |.|:..||::..:.||.|.             |...
  Rat   420 -GRDELTMAVRKELTVAVRDLLAHGLY--ASSSGMSLVMAPIACLLPA-------------FSSA 468

  Fly   569 GRAMHAWELVLAYYRLKHGEEYNNTPARKLSQSFQLDIVDAQAVTAKQSLLSAVGMILAMHRPYK 633
            ...||.|||.:.||..|:|..|..:|||||||||.|.|:...|||.|||||:|:.::|..|.|:|
  Rat   469 PETMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPIMGDAAVTPKQSLLTAIHLVLTEHDPFK 533

  Fly   634 RSNNAHFKAFVCAGLNSHLLVEWLNLILSCHELVDTYYSADSYVARTGFRDSLRSIDALSRFDFD 698
            ||.::..||.||..||...||.|:|||.....|::.:|...||:|.|||..:|..:..||...|.
  Rat   534 RSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFS 598

  Fly   699 LPVDLAIRHFRNI 711
            ||||||:|..:||
  Rat   599 LPVDLAVRQLKNI 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3703	NP_569874.1	RUN_RUNDC1	253..700	CDD:439045	134/447 (30%)
Rundc1	NP_001385698.1	COG4913	<82..>281	CDD:443941	89/199 (45%)
		RUN_RUNDC1	266..583	CDD:439045	129/430 (30%)