DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Appl and WFDC8

Sequence 1:NP_001245448.1 Gene:Appl FlyBaseID:FBgn0000108 Length:890 Species:Drosophila melanogaster
Sequence 2:XP_016883608.1 Gene:WFDC8 HGNCID:16163 Length:247 Species:Homo sapiens

Alignment Length:170 Identity:40/171 (23%)
Similarity:58/171 (34%) Gaps:68/171 (40%)


  Fly    70 CLRDKM----DLLDYCKKAYPNRDITNIVESSHYQKIGGW-CRQGALNAAKCKGSHRWIKPFRCL 129
            |.::::    :|.|.|     |.|.    :...|||...: |::                  :|:
Human    51 CPKERLTCTTELPDSC-----NTDF----DCKEYQKCCFFACQK------------------KCM 88

  Fly   130 GPFQSDALL-VPEG-CLFDHIHNAS---------RCWPFVRWNQTGAA-------ACQERGMQMR 176
            .|||...:| |..| |    .|.|.         ||.||......|.|       ||       |
Human    89 DPFQEPCMLPVRHGNC----NHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC-------R 142

  Fly   177 SFAMLL----PCGISVFSGVEFVCCPKHFKTDEIHVKKTD 212
            :..||:    .|.:..|:  |...||....:| |...:||
Human   143 TACMLIVKDGQCPLFPFT--ERKECPPSCHSD-IDCPQTD 179

Known Domains:


GeneSequenceDomainRegion External IDIdentity
ApplNP_001245448.1 A4_EXTRA 26..198 CDD:128326 35/155 (23%)
APP_N 33..141 CDD:280358 16/77 (21%)
APP_Cu_bd 143..198 CDD:289676 18/75 (24%)
APP_E2 387..580 CDD:289677
GBP_C <629..682 CDD:303769
APP_amyloid 834..887 CDD:287486
WFDC8XP_016883608.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG4295
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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