DRSC/TRiP Functional Genomics Resources

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Protein Alignment ase and HAND1

DIOPT Version :10

Sequence 1:NP_476694.1 Gene:ase / 30985 FlyBaseID:FBgn0000137 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_004812.1 Gene:HAND1 / 9421 HGNCID:4807 Length:215 Species:Homo sapiens


Alignment Length:158 Identity:43/158 - (27%)
Similarity:58/158 - (36%) Gaps:56/158 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   114 PAKKCKTNKKLAVERP----------------PKAGTISHPHKSQSDQSFGTPGRKGL------P 156
            ||.:|..      |||                |..|  ..|..:.:..::|...|.|.      .
Human    31 PASRCHQ------ERPYFQSWLLSPADAAPDFPAGG--PPPAAAAAATAYGPDARPGQSPGRLEA 87

  Fly   157 LPQAVARRNA----RERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAV 217
            |...:.||..    :||.|.:.:|:.||.|||.||..            .|..||||::|||:|.
Human    88 LGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNV------------PADTKLSKIKTLRLAT 140

  Fly   218 EYIRSLEKLLGFDFPPLNSQGNSSGSGD 245
            .||..|..:|..|          :.|||
Human   141 SYIAYLMDVLAKD----------AQSGD 158

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
aseNP_476694.1 bHLH_TS_dAS-C_like 170..227 CDD:381587 21/56 (38%)
HAND1NP_004812.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 53..109 12/57 (21%)
bHLH_TS_HAND1 94..153 CDD:381522 26/70 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 166..198
Blue background indicates that the domain is not in the aligned region.

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