Protein Alignment sc and ASCL5

DIOPT Version :10

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001257530.1
• Gene: ASCL5 / 647219
• HGNCID: 33169
• Length: 206
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 56/206 - (27%)
• Similarity: 76/206 - (36%)
• Gaps: 78/206 - (37%)

  Fly    40 IMPAP--SPLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAPYNVD------ 96
            :||.|  :||.|.    :|.|.:|.                    .|.||.:..|| .|
Human    25 VMPPPRQAPLPPA----EPLGNVPF--------------------LLYPGPAEPPY-YDAYAGVF 64

  Fly    97 ----------------QSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKK 145
                            :...:|:||.|||.|||.||..:||||.|:|           |....|:
Human    65 PYVPFPGAFGVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLP-----------GALAEKR 118

  Fly   146 ISKVDTLRIAVEYIRRLQDLVDDLNGGSNIGANNAVTQLQLC------------------LDESS 192
            :|||:|||.|:.||:.||:|:.....||...|:..:.....|                  ...|.
Human   119 LSKVETLRAAIRYIKYLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSL 183

  Fly   193 SHSSSSSTCSS 203
            ...||.|:|.|
Human   184 VPESSESSCFS 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	bHLH_TS_dAS-C_like	100..166	CDD:381587	30/65 (46%)
ASCL5	NP_001257530.1	bHLH_TS_ASCL5	79..139	CDD:381590	30/70 (43%)