Protein Alignment sc and NEUROD6

DIOPT Version :10

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_073565.2
• Gene: NEUROD6 / 63974
• HGNCID: 13804
• Length: 337
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 63/265 - (23%)
• Similarity: 95/265 - (35%)
• Gaps: 94/265 - (35%)

  Fly   102 QRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLV 166
            |..|||||||:..:|::...||:.:|....|           :|:||::|||:|..||..|.:::
Human    97 QEANARERNRMHGLNDALDNLRKVVPCYSKT-----------QKLSKIETLRLAKNYIWALSEIL 150

  Fly   167 ------DDLNGGSNI--GANNAVTQLQL-CLD------------ESSSHSSSS-ST--------- 200
                  |.|....|:  |.:...|.|.. ||.            |::.|:.|. ||
Human   151 RIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQGGEAAHHTRSPYSTFYPPYHSPE 215

  Fly   201 -CSSSGHNT------------------YYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVG 246
             .:..||.|                  :|::|   ||     :....|| ..||:...:|.|
Human   216 LTTPPGHGTLDNSKSMKPYNYCSAYESFYEST---SP-----ECASPQF-EGPLSPPPINYN--- 268

  Fly   247 TSVPGGDAGCVSTSKNQQTCHSPTSSFNSSMSFDSGTYEGVP------QQISTHLDRLDHLDNEL 305
                    |..|..:.:...:.  .::|..|.     |..||      |.....|....|...:|
Human   269 --------GIFSLKQEETLDYG--KNYNYGMH-----YCAVPPRGPLGQGAMFRLPTDSHFPYDL 318

  Fly   306 HTHSQ 310
            |..||
Human   319 HLRSQ 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	bHLH_TS_dAS-C_like	100..166	CDD:381587	23/63 (37%)
NEUROD6	NP_073565.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..82
		Nuclear localization signal. /evidence=ECO:0000255	80..86
		bHLH_TS_NeuroD6_ATOH2	82..151	CDD:381565	23/64 (36%)
		Neuro_bHLH	153..272	CDD:463621	27/138 (20%)