Protein Alignment sc and NEUROG2

DIOPT Version :10

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_076924.1
• Gene: NEUROG2 / 63973
• HGNCID: 13805
• Length: 272
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 64/282 - (22%)
• Similarity: 105/282 - (37%)
• Gaps: 75/282 - (26%)

  Fly    11 TTMSSSVLSTNETFPTTINSATKIFRYQHIMPAPSPLIPGGNQNQPAGTMPI--KTRKYTPRGMA 73
            |.:|||.....|..|.....|.:....:....|...:..|....:||..:.:  ..::...|..|
Human    31 TPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARA 95

  Fly    74 LTRCSESVSSLSPGSSPAPYNVDQSQSVQR--------RNARERNRVKQVNNSFARLRQHIPQSI 130
            ::|.:::                 :::|||        .|.|||||:..:|.:...||:.:| :.
Human    96 VSRGAKT-----------------AETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP-TF 142

  Fly   131 ITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQD---LVDDLNGGSNIGANNAVTQLQLCLDESS 192
            ..|          .|::|::|||.|..||..|.:   |.|...||.. |...|:....:.|
Human   143 PED----------AKLTKIETLRFAHNYIWALTETLRLADHCGGGGG-GLPGALFSEAVLL---- 192

  Fly   193 SHSSSSSTCSSSGHNTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCV 257
            |...:|:..||||.:....:|.|.:              :.|..:.|:::|
Human   193 SPGGASAALSSSGDSPSPASTWSCT--------------NSPAPSSSVSSN-------------- 229

  Fly   258 STSKNQQTCHSPTSSFNSSMSF 279
            |||....|. ||.|...|.|.:
Human   230 STSPYSCTL-SPASPAGSDMDY 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	bHLH_TS_dAS-C_like	100..166	CDD:381587	23/76 (30%)
NEUROG2	NP_076924.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..69		8/37 (22%)
		bHLH_TS_NGN2_ATOH4	104..172	CDD:381560	24/78 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..264		19/83 (23%)