Protein Alignment sc and ASCL3

DIOPT Version :10

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_065697.1
• Gene: ASCL3 / 56676
• HGNCID: 740
• Length: 181
• Species: Homo sapiens
• Alignment Length: 133
• Identity: 40/133 - (30%)
• Similarity: 58/133 - (43%)
• Gaps: 46/133 - (34%)

  Fly    41 MPAPSPLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAPY----NVDQSQS- 100
            :|.||..:..||.::|.                            |.|.|.||    ..:.|..
Human    56 LPFPSDSLILGNYSEPC----------------------------PFSFPMPYPNYRGCEYSYGP 92

  Fly   101 --VQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQ 163
              .::||.|||.|||.||..:|:||.|:|:..:           .|::|||:|||.|::||..||
Human    93 AFTRKRNERERQRVKCVNEGYAQLRHHLPEEYL-----------EKRLSKVETLRAAIKYINYLQ 146

  Fly   164 DLV 166
            .|:
Human   147 SLL 149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	bHLH_TS_dAS-C_like	100..166	CDD:381587	27/68 (40%)
ASCL3	NP_065697.1	bHLH_TS_ASCL3	91..149	CDD:381588	27/68 (40%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	93..106		5/12 (42%)
		Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	107..145		18/48 (38%)