DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hoxb3a and zen2

DIOPT Version :9

Sequence 1:	NP_571192.2	Gene:	hoxb3a / 30339	ZFINID:	ZDB-GENE-990415-104	Length:	417	Species:	Danio rerio
Sequence 2:	NP_476794.1	Gene:	zen2 / 40827	FlyBaseID:	FBgn0004054	Length:	252	Species:	Drosophila melanogaster

Alignment Length:	110	Identity:	53/110 - (48%)
Similarity:	72/110 - (65%)	Gaps:	19/110 - (17%)

- Green bases have known domain annotations that are detailed below.

Zfish   156 SSPSASSANAESSGGEKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLS 220
            ::|:|::.::|.            |||:|||::|.||:|||:|||.|:||.|.||:|::..|.|:
  Fly    31 AAPTATTRSSEK------------SKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALT 83

Zfish   221 ERQIKIWFQNRRMKYKKDQKSKG-IGSSSGGPSPTGSPPLPMQSS 264
            |||:||||||||||.||....|| ||:.      |.|.||..|||
  Fly    84 ERQVKIWFQNRRMKLKKSTNRKGAIGAL------TTSIPLSSQSS 122

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hoxb3a	NP_571192.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..135
		Antp-type hexapeptide	140..145
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	147..184		6/27 (22%)
		Homeobox	184..236	CDD:278475	34/51 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	237..290		12/29 (41%)
		DUF4074	353..415	CDD:290032
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..417
zen2	NP_476794.1	Homeobox	46..99	CDD:278475	34/52 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.770