Protein Alignment Thg1l and THG

DIOPT Version :10

• Sequence 1: NP_001013988.1
• Gene: Thg1l / 303067
• RGDID: 1359513
• Length: 298
• Species: Rattus norvegicus
• Sequence 2: NP_609737.1
• Gene: THG / 34876
• FlyBaseID: FBgn0283659
• Length: 286
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 150/265 - (56%)
• Similarity: 188/265 - (70%)
• Gaps: 19/265 - (7%)

  Rat    30 MAKSKFEYVRDFEVDDTCLPHCWVVVRLDGRNFHRFAEKHNFAKPNDSRALHLMTKCAQTVMQEL 94
            ||.|:||||:.||.||:.||:.|:|:|:||:.||:|::.|:|.||||..||::|...|..||||.
  Fly     1 MACSRFEYVKSFEQDDSILPNVWIVIRIDGKKFHKFSKTHDFEKPNDENALNVMNAAATAVMQEF 65

  Rat    95 EDIVIAYGQSDEYSFVFRKRSNWFKRRASKFMTLVASQFASSYVFYWRDYFEDQPLLYPPGFDGR 159
            .|||:||||||||||||||.:..||||::|.:|.|.|.|:||||..|..:. :.||.|.|.||||
  Fly    66 RDIVLAYGQSDEYSFVFRKETAAFKRRSAKLLTYVTSLFSSSYVMQWSKWM-NLPLAYAPCFDGR 129

  Rat   160 VVLYPSNQTLKDYLSWRQADCHINNLYNTVFWALIQQSGLTPVQAQQRLKGTLTADKNEILFSEF 224
            ||||||.|.|||||||||||.|:||||||.||.|:.:.|||..||:.:|:||.:|||||:||.||
  Fly   130 VVLYPSEQNLKDYLSWRQADVHVNNLYNTAFWKLVLEKGLTNQQAEAKLRGTFSADKNELLFQEF 194

  Rat   225 HINYNNEPHMYRKGTVLVWQKVNEVRTQEIRLPAEMEGEKMAVTRTRTKLVALNCDLIGDAFWKE 289
            .|||||.|.||||||:|:.::|             :.|||     :|..:|.|:.|||...||||
  Fly   195 GINYNNLPAMYRKGTILLRKRV-------------ILGEK-----SRQAVVPLHEDLISSQFWKE 241

  Rat   290 HPEIL 294
            |.|||
  Fly   242 HTEIL 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Thg1l	NP_001013988.1	Thg1	35..164	CDD:461314	74/128 (58%)
		Thg1C	167..283	CDD:464167	61/115 (53%)
THG	NP_609737.1	Thg1	6..134	CDD:461314	74/128 (58%)
		Thg1C	137..234	CDD:464167	60/114 (53%)