Protein Alignment Atp10b and CG33298

DIOPT Version :10

• Sequence 1: NP_001415672.1
• Gene: Atp10b / 303056
• RGDID: 1565126
• Length: 1472
• Species: Rattus norvegicus
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1412
• Identity: 556/1412 - (39%)
• Similarity: 810/1412 - (57%)
• Gaps: 194/1412 - (13%)

  Rat    15 RSQNGFSQSPSETTP------LLSPETGRQSYNPTEQRVVYPNNSMCHQDWKK--VSRRYPGNSI 71
            ||::.::...:|..|      |.:..|| ..:.....|.|.||:::..:..|:  .:.::.||.|
  Fly   192 RSESIYTLRRTEAPPWWKRLTLCNYNTG-DKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKI 255

  Rat    72 CTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLLVIMVKDGTE 136
            .|||||||:|:|:||.|||||.|||||:|:|:|||:|.:..|.:|:.|:|:..||.|..|||..|
  Fly   256 RTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFE 320

  Rat   137 DFKRYCFDREMNSASIQIYERKEQSYMQKRWQDVRVGDFVQMRCNEIVPADILLLFSSDPSGVCH 201
            |.:|...|:.:|:.:.::|:.:.:.|.:.:||::||||.|.:..||.||||||||.:|||.|||:
  Fly   321 DRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCY 385

  Rat   202 LETANLDGETNLKQRRVVKGFSQQEVQFQPEHFHSTIVCEKPNNHLSKFKGYMEHPDETRTGFGS 266
            ::|.:||||||||:|.||:||.:.:..|.|..|.|.:..:.|...|.:|.|.:.||...|....:
  Fly   386 IDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPTGERVPIST 450

  Rat   267 ESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIG 331
            |.||||...::||:...|||:|||||||:||||||||||||::|:::|.|:.:|:.:|.::|::|
  Fly   451 ECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVG 515

  Rat   332 AVGHSLWNGTFKEHPPFDVPDADGNFLSPALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVF 396
            |:|..:|..:|...|   ||....|.|:..:...::|.|.|::|||:||:||||:|||.|:.|||
  Fly   516 AIGCRMWLSSFTHFP---VPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVF 577

  Rat   397 LLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGNEYCHQENA 461
            .:||::||:|.||:...:|||:||||:|||||:||:|||||||||||:||||.:.|::|.|.
  Fly   578 HIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHP--- 639

  Rat   462 KRLEMPKELDSDGEEWTQYQCLSFPPRWTQGPATIRSQGGAQPLRRCHSARVPIQSHSRQRSVGR 526
                 |.||:.                       |.|:.||
  Fly   640 -----PSELEK-----------------------IYSKPGA------------------------ 652

  Rat   527 WETSQPPVAFSSSIEKDVTPDKNLLSKVRDAALWLETLDTRPAKPSHSTTASIADFFLALTICNS 591
               ..||          :.|:.||.|.:  |.|...|..|..|:       .|.:|.:.|.|||:
  Fly   653 ---PAPP----------LIPNDNLNSDM--AQLTQGTYLTPHAQ-------RIQEFLVVLAICNT 695

  Rat   592 VMVSTTTEPRKRVTTPPA---NKALGTSLEKIQHLFQRLKLLSLSQSFSSTAPSDTDL-GESLGP 652
            |:|...  |.:.:.....   .:.:|.|...::|..||.|||:   |.:||..:.|.: |.:..|
  Fly   696 VIVGAA--PHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLA---SSTSTTTTTTIINGPTTQP 755

  Rat   653 NVPTIDADE----KDDASVCSGD------CSTDGGYR------SSTWEQGDNLGSESG------- 694
            .|.:|.||.    .:..||....      ......::      ||:.|...|..|||.
  Fly   756 QVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNK 820

  Rat   695 --------------------TSLEEGLEAPA----------------LSLDGPELCYEAESPDEA 723
                                ||:...|.|..                .:.||..| ||||||||.
  Fly   821 SLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPL-YEAESPDEL 884

  Rat   724 ALVHAARAYSFTLVSRTPEQVTVRLPQ-GICLTFDLLFTLGFDSVRKRMSVVVRHPLTGEIVVYT 787
            |||:||.:|...|::|:|.|:.|.:|. |....:::|..|.|||.||.||:|||...:.|||:||
  Fly   885 ALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYT 949

  Rat   788 KGADSVIMDLLEDPACGNDIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVNEEDFQRWAS 852
            |||||.||.:|. |...|..:     ..:|.:||:.||.|||:|||.|.:||:.:|..|:..|.:
  Fly   950 KGADSSIMPVLV-PCSHNSPE-----GILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWA 1008

  Rat   853 FRREAEASLDNREELLMETAQHLENRLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQ 917
            ..:|.|.||:|||..|.::...||:.||||||||||||||:|||:|||:|..|||.:|||||||.
  Fly  1009 RHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKP 1073

  Rat   918 ETAVNVAHSCKLLDQADTVYSINTENQETCESILNCALEDVKRFHEPQQPARKLCGYCIPSKKPS 982
            |||:|:|:|.||..|...:..:...:::..|:.:|..|.|::     ........||....:|
  Fly  1074 ETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDME-----NDKTTSTLGYGQSLRK-- 1131

  Rat   983 VNLGAMAPEIGLVIDGKTLNAIF--QGKLENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLS 1045
                   .:..||:|||||..|.  :.||...||.|::.|.||||||||||||:.:||:|:::|:
  Fly  1132 -------KQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELN 1189

  Rat  1046 VMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARM 1110
            :.||:||||||||||||.||:|:||||||||||||::||.:.||.:|::|||.||:|||.||:||
  Fly  1190 LRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRM 1254

  Rat  1111 VVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIVFGILDKDVSAETLLAL 1175
            ::|:||||..:|.|:||||.:|||||..|:|...::.:||.||||||:..|:.||.|:.:.||..
  Fly  1255 ILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKN 1319

  Rat  1176 PELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLH 1240
            |.|||:|:....|....||:.:.||.||||:.||:....|..||:.::.|||.|....|...|:|
  Fly  1320 PYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVH 1384

  Rat  1241 QAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPTNPYWLMERQLSDPMFYLTCLLTPV 1305
            .|:|:::|||||.|.::.|...:::.:::|::.|:.|....:.||::....:..:.:|..:|:.|
  Fly  1385 CAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTV 1449

  Rat  1306 VALLPRYFLLSLQGTYGKSLISKAQKIDKLPIDKRNLEIQNWRSKQR 1352
            ||:|||..|.::             :|...|.|...:.:|:.|.:.|
  Fly  1450 VAVLPRLLLTTV-------------RISLCPDDSTKVILQSKRERSR 1483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atp10b	NP_001415672.1	None
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	505/1208 (42%)